VETEEINABY MEDICIlSrE. 483 



ment, and those to be given protection received 50 cc. of vaccine and 100 cc. 

 of the sernm. 



The method was applied in 3 barns, the first containing 20 horses, of which 

 1 was dead, another died 1 day after treatment, and 5 were strongly diseased; 

 and the second contained 48 horses, of which 1 died, 5 were diseased, and 2 had 

 a slight fever. The third consisted of 2 stables holding 40 animals each, in 

 1 of which 2 animals were dead and 4 were diseased, while in the other the 

 animals were sound and received no treatment. In the first barn 12 animals 

 given protective vaccination did not take the disease; in the second, 38 remained 

 sound ; and in the third, 34 were sound and 4 of those diseased recovered. Of 

 the 40 control animals, i. e., those receiving no vaccination, only one showed a 

 slight febrile condition, and this after a few weeks. No complications followed 

 the treatment. The method is thought to be a good one for protective vacci- 

 nation purposes. 



Protective and curative tests in the pectoral form of equine influenza, K. 

 NowACKi {Berlin. Tierdrztl. Wchnschr., 29 {1913), No. 13, pp. 235-2SG).— A de- 

 scription of outbreaks in 2 barns, one containing 58 horses of which 18 had more 

 or less marked symptoms of equine influenza ; the other barn contained 48 

 horses, 5 of which had marked symptoms of the disease. Three of the animals 

 died previous to treatment. 



The 40 apparently sound horses in the first barn received 100 cc. of Pfeiler's 

 serum and 50 cc. of vaccine given intravenously. Directly after vaccination no 

 untoward effects were noted, but after one-half hour the horses became restless, 

 perspired, developed tremors, and some discharged feces. After 2 hours most 

 of the horses were down and refused to take feed. The lack of appetite per- 

 sisted on an average for 48 hours, and during this time the horses could not be 

 worked. The temperature rose from 0.5 to 0.8° C. above the normal. One of 

 the horses died on the third day after giving the vaccine, but as a result of colic 

 and tympanites; no pneumonia was found on section. In addition, seven 4-year- 

 old foals were treated. Only 2 of the animals given protective treatment be- 

 came affected with infiuenza, and these recovered. Of the 18 horses affected 

 with influenza and given curative treatment 5 died. 



The second group of animals was treated in the same manner, the diseased 

 horses receiving only serum and those apparently unaffected, vaccine plus 

 serum. Four days after vaccination 5 more cases developed among the appar- 

 ently sound animals, but none of the 40 animals treated protectively died, while 

 1 of the 5 given curative treatment succumbed. 



The author believes that the serum-vaccine treatment is a valuable method 

 for immunizing animals against this disease. 



Equine piroplasmosis in the Canal Zone, S. T. Darling {Science, n. ser., 31 

 {1913), No. 949, pp. 370, 371). — The author reports the occurrence of this dis- 

 ease in an American driving horse wlilch had been on the Isthmus for several 

 years. This animal is thought to have become infected from Dermncentor nitens 

 while driven out into Las Sabanas to the Juan Diaz River. The parasite 

 closely resembles Piroplasma cahalli and differs from Nuttallia eqiii in not dis- 

 playing "cross forms." See also a previous note (E. S. R., 29, p. 83). 



Infection of the dog- with piroplasmosis through the mucous membranes, 

 N. N. Navrotzky {Centbl. Bakt. [etc.], 1. AU., Orig., 66 {1912), No. 5-6, pp. 

 417-Jf20; als. in Trop. Vet. Bill, 1 {191S), No. 3, p. I4O).— AW of the 3 full- 

 grown dogs and 5 puppies to which diluted blood containing piroplasms was in- 

 troduced (1) by ingestion, and (2) directly into the stomach by means of a tube. 

 became infected. All of the puppies and one of the dogs succumbed to the 

 disease 



