1020] VETERTNAr.Y MEDirTNE. 381 



(•i|iiliii tost aro cnnc«>rne(l. Aitp.ircMtly, (lio forms fnmi the two hosts are 

 ItidcluMiiiciilly as well as luorpliolof^lcally iiulistiii;,'nisli:ihlo. Rniall quaiititU's 

 (if prcciititatin^ soniiii suflicicnt to cause the formation of precipitates in salt- 

 solution extracts of ascarids failed to produce precipitates in similar extracts 

 of unrehited nematodes (I)ictyocaulus, Strongylus). The results obtained 

 hy means of the anaphylactic test appear to be in a general way in agreement 

 witli the results of the precipitin test, although a considerable degree of varia- 

 tion was noted as regards the reactions of guinea-pigs to injections of similar 

 extracts. Definite conclusions from the experiments on anaphylaxis aro not 

 .instilled in view of the limited number of experiments." 



On the resistance of Ascaris o«j«:s, S. Yosiiida {Jour. Parasltol., 6 (1020), 

 No. 3, pp. lS2-l,i!)). — Data here presented have been substantially noted from 

 another source (E. S. 11., 43, p. 80). 



vStudios on anthelmintics. — VTTT, Some experiments with fluid extracts, 

 I\I. C. Ham, (Jour. Anicr. Vet. Med. As.wc, 57 (11)20), Xo. 2, pp. iS.J-/.S7).— 

 'fills is a report of investigations conducted in continuation of those previously 

 i.oted (K. S. 11., 42, p. 675). The results have been sunnnarized as follows: 



" The low taeniacidal value of fluid extract of kamala as compared with the 

 high taoniacidal value of powdered kamala, and the low ascaricidal value of 

 fluid extract of chenopodiuni as compared with the high ascaricidal value of 

 oil of clu-nopodinm, bear out the statement that fluid extracts are freqiiently 

 unsuitable as anthelmintics. Fluid extract yf spigelia and senna pntmises 

 little of value as an anthelmintic, and this is in agreement with Foster's 

 findings, published by Hall and Foster (191S) [E. S. K., 38, p. 883]. Fluid 

 extract of balsam poplar buds may prove to be effective against ascarids and 

 uninjurious when taken in large doses, but large doses of this drug, with the 

 l»recipitation of the resinous content on the buccal mucosa, are resented by 

 dogs and would not be attractive to man. Fluid extract of caulophyllum 

 did not receive sufficient test to draw conclusions on, but in the dose used it 

 was not very effective." 



Variations in the hydrogen-ion concentration in uninoculated culture 

 medium, L. G. Grack and F. Highhergeb (Jour. Infect. Diseases, 26 (1920), No. 

 5, pp. Jf57-462). — Daily determinations over a considerable period of time are 

 reported of the pH values of 1 per cent glucose broth and of plain broth kept in 

 test tubes and in flasks, in the incubator at 37° C, in the ice box, and at room 

 temperature. 



r.oth the plain broth and the glucose broth showed changing pH values, but 

 the variations were not nearly so great in the plain as in the glucose broth, 

 itulicating that the resulting acid formed by the breaking up of the glucose Is 

 tlie chief factor responsible for the changes in H-ion concentration. The con- 

 clusion is drawn that as the question of optimum reaction for the growth of 

 different organisms assumes greater imi)ortance it will become more im- 

 portant to take into accoimt the variations in H-hm concentration occurring 

 in a medium independent of the activities of bacteria and to determine 

 the reaction of the medium just before it is inoculated. 



The relation of the rate of absorption of antisen to the production of 

 immunity, M. W. Cook (.Tour. Immunol., 5 (1920), No. 1, pp. S9-/f9) .—The 

 antlior refers to the fact established by various workers that previoiis treat- 

 ment with an antigen confers upon an aiuTual an increased power of absorp- 

 tion for that antigen, and to the work of Smith and Cook (E. S. K.. 88, p. 4S2) 

 fhat .ibsmptinn of antigen in innmmized animals prociM'ds more rapidly than 

 in sensitized <ir normal animals, and reports an investigation of the tpiesflon 

 as to whether the process of immunity production is in any way dojiendent 



