386 EXPERIMENT STATION RECORD. 



The intrapalpebral test, which consists of the intradermal injection in the 

 lower eyelid of ordinary subcutaneous tuberculin (concentrated to 50 per cent 

 of its original volume) was applied to a number of animals known to be 

 affected with tuberculosis and others known by previous subcutaneous tests to 

 be free of the disease. In from 12 to 24 hours from the time of injection in 

 the animals affected with tuberculosis the development of an edema in the 

 lower eyelid was observed, which continued to increase in intensity until in 

 about 48 hours it reached its height, but persisted for 72 hours or even longer. 

 In some instances it extended almost in a circular form around the entire 

 orbital cavity, while in others it only affected the eye in a semicircular man- 

 ner, appearing as a puffy swelling which was perceptible from a considerable 

 distance. In severe reaction the conjunctiva became injected, with an in- 

 creased flow of tears and not infrequently a muco-purulent discharge — phe- 

 nomena which are similar to those in the ophthalmic reactions. 



" For diagnostic purpo.ses, however, the latter phenomena are not essential, 

 as the edema which persists for 48 hours after the injection is a sufficient 

 indication upon which to base a positive diaj5iM)sis of tuberculosis. In making 

 the observations anyone may readily observe the reaction from a distance of 

 from 25 to 50 ft. in the tuberculous animals, whereas in the healthy animals 

 there is no reaction whatsoever, both eyes having the same normal appearance. 



" In some instances the reaction was also accompanied by a more or less 

 pronounced systemic disturbance, indicated by an elevation of the temperature, 

 which varied from 2 to 4' above the preinjecting temperature. . . . The ad- 

 ministration of the tuberculin causes no difficulty and the small quantity of 

 the fluid required can be readily forced into the cutaneous tissues with a 

 proper syringe and needle." The dose of tuberculin to be injected is 0.25 cc, 

 which must be injected in the skin proper and not under the skin. 



" From the limiteil observations made on this test it appears that further 

 experimentation is justified ; and, should additional experience prove the test 

 to be sufficiently accurate for diagnostic purposes, it could be employed either 

 In place fif the subcutaneous or as a tost supplementary to the latter method." 



Tuberculosis in pheasants, E. M. Pickens (.Cornell Vet., 4 {1915), Xo. J^, 

 pp. 1S3-190, figs. S). — The author reviews the literature and reports upon an 

 outbreak of this disease in New York State. 



The puerperal diseases of cattle and their relation to meat poisoning, A. 

 VoiGT {Die pucrperalen Erkrankiingen des Rindes und ihre Bezichungcn cm den 

 Flcisctivcrgiftungcn. Inaug. Diss., Unit-. F.eipsic, 1912, pp. 89). — This discussion 

 of the subject includes a bibliography of 212 titles. 



Recent investigations on contagious abortion, T. Kitt {Mon(it.t7i. Prakt. 

 Ticrhcilk.. 26 {191^), No. 5-4. pp. 164-174; ab.9. in Cornell Vet., 5 {1915), No. 1, 

 pp. 61, 62). — A general review and discussion of the subject with 26 references 

 to the literature. 



Sidelights on contagious abortion, W. L. Williams {Cornell Vet., 5 {1915), 

 No. 1, pp. 25-47). — This account, basetl upon investigations previously noted 

 (E. S. R.. 31, p. 779), consists of a general discu.'^sion of the disea.<?e and tl»e 

 handling of it. together with an account of studies of the agglutination test 

 near parturition. 



A review of recent progress in hog cholera investigations. H. P. Hoskinh 

 {Jonr. Awer. Vet. }fed. Assoe., 4S {1915), No. 2, pp. 160-173). — A review of 

 recent work with references to the literature. 



The vacuum method of drawing antihog-cholera serum. T. P. Haslam, 

 A. E. Hagan, and R. V. CHRI.sTIA^f {Jour. Infect. Diseases, 16 {1915), No. S, 

 pp. 4S7-492, figs. 5). — The authors here describe and illustrate a system which 

 has been devised as a result of a series of exi)erimenta at the Kansas Expert- 



