VETEEINAEY MEDICINE. 479 



cemia in New York State. These have led to the conclusions that " the symp- 

 toms of septicemia hemorrhagica could easily be confused with those of certain 

 nonspecilic infections; that a careful bacteriological examination, including 

 animal inoculation of fresh specimens, should be made of all cases in which 

 septicemia hemorrhagica is suspected ; and that a further and extensive re- 

 search must be done in order to determine the exact relationship of the bac- 

 teria which comprise the so-called septicemia gi'oup or pasteurella." 



Directions for constructing vats and dipping cattle to destroy ticks, H. W. 

 Geaybill and \Y. P. Ellenberger (17. S. Dept. Agr., Bur. AnUn. Indus. Giro. 

 207, rev. ed. {1915), pp. 22, figs. 3). — A revised edition of the circular pre- 

 viously noted (E. S. R., 28, p. 181). A plan for a concrete vat for range con- 

 ditions has been added. 



The etiology of •" symptomatic anthrax " in swine. — " Specific gas-phleg- 

 mon of hogs," K. F. ]\Ieyee {Jour. Infect. Diseases, 11 {1915), No. 3, pp. 458- 

 496, figs. 5). — The author proposes the name of specific gas-phlegmon of hogs 

 for the disease here considered. " The methods and media recommended by 

 von Hibler [E. S. R., 20, p. 1080], the agglutination tests, and the serum im- 

 munization of guinea pigs proved to be very reliable for the separation and 

 identification of closely allied anaerobes. . . . 



" The study of this disease, additional experiments, and a critical survey of 

 the literature fail to prove that hogs are spontaneously attacked by symptomatic 

 anthrax, or that they are susceptible to Bacillus chauvwui." 



A bacteriologic study of secondary invaders in hog cholera, F. Ebebson 

 {Jour. Infect. Diseases, 17 {1915), No. 2, pp. 331-338). — " Organisms belonging 

 to the Bacillus paratyphosus group were chiefly associated with the lungs 

 and spleen of hogs infected with the virus of hog cholera. B. coli was fi'e- 

 quently found in the lungs and spleen, either alone or in combination with 

 organisms of the paratyphoid group. B. suisepticus was isolated in few cases, 

 but 9 out of 55, and was found chiefly in the intestine. 



" Classification of the organisms shows that the greatest number belonged 

 to the B. paratypliosus B group. The majority of these did not form indol and 

 were found chiefly in the lungs and spleen. Bacterial findings did not appear 

 to be correlated with the lesions observed in different organs. The significance 

 of secondary invaders in hog cholera is not apparent from a study of the lesions 

 and the dilTerent groups of organisms isolated." 



Separation of the antibody fractions in hog cholera serum, F. Ebeeson 

 {Jour. Infect. Diseases, 17 {1915), No. 2, pp. 339-350, figs. 2).—" Hog-cholera 

 serum can be split up by chemical means Into an actively protecting globulin 

 fraction and an inactive albumin fraction. Precipitation of serum proteins by 

 means of ammonium sulphate is practically possible for hog-cholera serum. 

 The bulk of the serum, being inactive albumin, may be dispensed with. 



"Concentration for practical purposes may be effected (1) by precipitating 

 the euglobulins from diluted serum, by means of 33J per cent saturation with 

 ammonium sulphate solution, filtering, making the filtrate up to 50 per cent 

 concentration with ammonium sulphate solution, filtering, and, after dialyzing 

 the precipitate in running water, dissolving it in the smallest volume of salt 

 solution; (2) by precipitating the diluted serum (diluted 10-15 times) by one- 

 half saturation with ammonium sulphate (saturated solution), filtering, dialyz- 

 ing the precipitate, and treating as in (1). Since both globulin constituents 

 are protective, this method would prove more economical and simpler. 



" Euglobulin represents from 20 to 21 per cent of the total serum protein, 

 pseudoglobulin 0.5 per cent, and albumin about SO per cent." 



