276 EXPERIMENT STATIOX RECORD. 



ducted, together with a review of tlie literature, a list of 26 references to which 

 is included. 



The author finds that the leucocytes of the horse possess the property of 

 neutralizing diphtheria toxin and that this capacity does not depend upon the 

 physicochemical property of their protoplasm but upon their activity. The 

 leucocytes of the horse are capable neither of absorbing nor of neutralizing 

 the tetanus toxin. Only leucocytes of the rabbit which contain from 15 to 20 

 per cent of macrophages possess this property and their effect is not very 

 pronounced. The leucocytes are the defenders of the organism in its fight 

 against pathogenic agents and their toxins and determine the natural immunity 

 against the latter. 



Parasitism and Eosinophilia, D. E. Paxtlian {Compt. Rend. Soc. Biol. 

 [Paris], 78 (1915), Xo. 7, pp. 155, 156). — The author finds that helminth toxins 

 sensitize the organism and the anaphylaxis causes the eosinophils to appear, it 

 being their part to defend the organisms against the toxins just as the poly- 

 nuclears defend against the microbes. 



The recognition of atypical forms of blackleg in the United States, K. F. 

 :Meyer {Upt. v. S. Lire Stock Sanit. Assoc, 18 (1915), pp. 91-98). — "Attention 

 is called in this note to the occurrence in this country of * atypical ' blackleg. 

 The term is used to specify that blackleg can occur in cattle without showing 

 the lesions published in text-books and commonly emphasize<l to students and 

 the laity. The pathologic-anatomical lesions (particularly in the internal or- 

 gans, as liver and pleura) are far more multiform than suspectetl. It is essen- 

 tial that complete autopsies be made on all cattle; also, sporadic cases often 

 offer valuable information and enable the sanitary officer to prevent further 

 losses. The methods of diagnosis are cited and e.xplained. 



"The occurrence of blackleg affections in hogs in this country (in Pennsyl- 

 vania) is reported. As a causative agent, the so-called Ghon-Sachs bacillus 

 has been found. These results are confirmed by the work of Koves in 

 Hungary." 



Contributions to the serodiagnosis of glanders; the technique of the K. H. 

 reaction in diagnosing glanders, \V. Pfeiler and F. Scheffler {Berlin. 

 Tierdrztl. M'rhnsclir., 31 (1915), Xo. 11, pp. 12 1-1 2 If). —The K. H. (conglutina- 

 tion-hemolysis) reaction of Pfeiler and Scheyer is a reaction in which there is 

 hemagglutination and deviation of complement at the same time. If condi- 

 tions are unfavorable for complement fixation, hemolysis occur.s. 



In a study of over 5,000 sera, some were found which did not give the agglu- 

 tination, complement fixation, or conglutination reactions, but which gave the 

 K. H. reaction. The K. H. test seems to be adapted to the diagnosis of chronic 

 cases of glanders. Cases were found which did not give the K. H. reaction, 

 but gave results with the complement fixation method. 



Trichinosis, B. H. Ransom (Rpt. U. S. Live fitock Sanit. Assoc., 18 (1915). 

 pp. 147-165). — Following accounts of the parasite TrichineUa spiralis and the 

 disease caused by it, the author discusses sources of infection, prevalence of 

 trichinie in hogs, effects of heat, low temperatures, and salt upon trichin.np. and 

 prophylaxis. 



Experiments in the " tryposafrol " treatment of trypanosomiasis (Trjrpa- 

 nosoma brucei) in guinea pigs and of piroplasmosis in dogs, G. H. F. Nuttall 

 and E. Hindle (Parasitology, 8 (1915), No. 2, pp. 218-228).— In tests here 

 reported both tryposafrol and novo-tryposafrol exerted a directly injurious 

 effect upon guinea pigs infected with T. brucei. Four dogs infected with 

 Piroplasma cams died, although treatment with novo-tryp-osafrol was given 

 under the most favorable conditions, starting on the date of inoculation. " The 

 drug exerted no influence upon the course of the disease nor upon the appearance 



