574 EXPERIMENT STATION RECORD. [Vol.41 



for the years 19u8 to 1915 were fair wider the ooiulitions then operating, and 

 recommended that the new price be the average price of this period plus a 

 percentage increase equal to the relative increase in the cost of feed and labor. 

 Beport of Chicago Milk Commission {Creamery and Milk Plant Mo., 7 (I'JIS), 

 No. 3, pp. 17-22). — The text of the majority report of the commission referred 

 to above is printed, together with a minority report by W. J. Kittle, and state- 

 ments by E. Davenport and P. G. Holden, two members who refused to vote in 

 favor of the majority report. 



VETERINAPvY MEDICINE. 



The influence of deficient nutrition on the production of agglutinins, com- 

 plement, and amboceptor, S. S. Zilva {Biorheni. Jour., 13 (1919), No. 2, pp. 

 172-19Jt, figs. 8). — The author suggests the urgency of a systematic study of the 

 influence of nutrition on the production of immunity, and contributes to this 

 study the report of an investigation of the effect of deficient diets on ambo- 

 ceptor and agglutinin formation and complement content. The influence of the 

 following dietetic deficiencies was studied; (1) diets low in ii-on, calcium, potas- 

 sium, sodium, chlorin, and phosphorus, respectively; (2) diets containing 12 

 per cent and 8 per cent of caseinogen as a source of protein; (3) diets con- 

 taining 18 per cent of gliadin as the sole source of protein; and (4) diets 

 deficient in each of the three accessory food factors. The influence of the quan- 

 titatively restricted diet on the complement content was also studied. Rats 

 were employed for the investigation of the action of deficient proteins, re- 

 stricted mineral salts, and accessory food factors on the production of ambo- 

 ceptor and agglutinins, and guinea pigs for the study of the influence of quantita- 

 tively restricted diets on the complement content of the blood and the influence 

 of a diet restricted in antiscorbutic factor on the production of amboceptor and 

 agglutinins. The technique employed and experimental data obtained are 

 described in detail and illustrated by tables and charts. 



" Although several of the deficiencies became manifest by the restricted 

 growth and the poor condition of the animals, no differentiation in the titers 

 of the agglutinins and amboceptor could be recorded, except in the group re- 

 ceiving the diet low in phosphorus. Guinea pigs fed on an unrestricted mixed 

 diet, quantitatively restricted mixed diet, and a scorbutic diet, showed no differ- 

 entiation in the amboceptor and agglutinin titers, or in the complement activity 

 of the blood." 



The author states in conclusion that the results of the experiments can at 

 present be considered only an indication, and that further investigation is 

 necessary in order to establish the fact definitely that a diet low in phosphorus 

 is the only one showing a well marked differentiation in the production of 

 agglutinins and amboceptor. 



Growth accessory substances for pathogenic bacteria in animal tissues, 

 I. J. Kligler {Jour. Expt. Med., 30 {1919), No. 1, pp. 31-U).— The object of the 

 investigation reported was to determine (1) the effect of vitamins on the 

 growth of a number of organisms pathogenic for man, (2) tlie distribution 

 of these substances in animal tissues, and (3) the relative significance of the 

 fat-soluble A and water-soluble B factors in the cultivation of these micro- 

 organisms. 



The organisms studied included the meningococcus, pneumococcus, strepto- 

 coccus, Bacillus diphtheriw, B. pertussis, and B. influensce, and in the course of 

 the Investigation beef heart, goat blood, rabbit and cat tissues, and human 

 secretions (nasal secretion and saliva) were used. Extracts of the tissues 

 with saline solution were added in graded amounts to nutrient broth or agar, 



