768 EXPERIMENT STATION RECORD. [Vol.41 



442). — This paper deals with the age at tleath of those mice in the authors' 

 experiments which reached adult life (age of 210 days). In the case of the 

 groups of animals fed either pituitary tissue, lecithin, or cholesterol, the devia- 

 tions of the average length of life from the average of normal adults were 

 found not to be much, if any, greater than the probable errors of tlie differences. 

 However, tlie males fed tethelin lived on tlie average 00 days (13 per cent) 

 longer than normal males, and the females which had received tethelin lived 

 81 days (11 per cent) longer than the control females. 



XIII. Lesions exhibited by normal, pituifarii-. leriffiiir-, cholesterol-, and 

 tethelin-fed ivhite mice at the occurrence of natural death, vith especial refer- 

 ence to the incidence and development of spontaneous cancer (pp. 443-4.53). 



XIV. Further experiments on the influence of tethelin upon the growth of 

 the ivhite mouse (pp. 4.5.5-463). — Report is made of the first 50 weeks' growth 

 of 48 female mice (born in 1016) fed tethelin in daily doses continuously, and 

 of the first 30 weeks' growth of 24 females (1016) and 22 males (1917) fed 

 tethelin from the fourth to the twelfth week of life only. 



All three groups showed the characteristic retardation in the adolescent 

 stage which normally is the period of most rapid growth. The curve of the 

 continuously-fed group remained below the normal curve until late in life, 

 when the postponement of senescence typical of tethelin feeding caused the 

 curve to meet the descending normal cui-ve. The other two groups after the 

 administration of tethelin had ceased shot rapidly above the normal, and 

 remained above throughout the period under consideration. This acceleration, 

 already noted to a much less marked degree in the two tethelin groups of 

 Study IV, is not attributed to the tethelin directly, but to " compensatory 

 factors which develop in the animal itself in response to the abnormal dosage 

 of the active principle of the anterior lobe of the pituitary body." It is stated 

 that some exceptionally large animals have been secured as the result of brief 

 periods of tethelin feeding. 



The growth of the ovarian follicle of the guinea pig under normal and 

 pathological conditions, L. S. N. Walsh (Jour. Expt. Med., 26 (1917), No. 2, 

 pp. 245-261, figs. 2). — The ovaries of 6 guinea pigs were cut into serial sections, 

 and the percentage of granulosa cells in the process of mitosis was deter- 

 mined for a number of normal follicles in different stages of growth. 



In small follicles (averaging 215 by 130/u.) 0.66 per cent of the cells were 

 dividing, in medium sized follicles (506 by 450/i) 1.2 per cent, in large follicles 

 (788 by eiV) 0.73 per cent, and in fully mature follicles (030 by 620/^) 0.06 

 per cent. About 220,000 cells were examined in making these determinations. 

 It is held that the growth energy is at its maximum in medium-sized follicles. 

 Most of the cell divisions were observed in the vicinity of the ovum. 



The extent of cell division in atretic follicles and in follicles of ovaries which 

 were not functioning normally was also studied. The proliferative power of 

 living granulosa cells is apparently reduced during the atresia which follows 

 ovulation. 



Live stock breeding, P. P. van der Poll (Jaarb. Dept. Landb., Nijv. en 

 Handel Nederland. Indie, 1916, pp. 291-333). — Inforniati(m is provided as to the 

 live stock interests of Java and Madura, Sumatra, Celebes, the Dutch posses- 

 sions in Borneo and most of the lesser East Indian Islands, but not of New 

 Guinea and the Molukka Islands, together with statistics of imports and ex- 

 ports, the numbers of cattle and buffalo slaughtered for meat, and the dis- 

 tribution of dairy cattle according to breed and locality. 



Famous Angus cows of Scotland, H. W. JIvmforo (Breeder's f!az., 76 (1919), 

 No. 11, pp. 462, 463). — The author selects five Aberdeen- Angus cows, Erica, 



