VETEEINARY MEDICIISTE. 277 



sera from the pregnant women showed high values, but certain neoplastic sera 

 gave increased tigures also. 



Glycosuria and allied conditions, P, J. Cammidge {London, 191S, pp. VII-{- 

 467, figs. 2). — This book, while dealing particularly with glycosuria, diabetes 

 Insipidius, etc., as they occur in man, is especially valuable for veterinarians in- 

 terested in diseases of metabolism. It deals with the classification, properties, 

 and physiology of the carbohydrates and their derivatives; the detection and 

 differentiation of sugars and other reducing substances in the urine; the deter- 

 mination of the sugars, acetone bodies, nitrogen, etc., in the urine ; experimental 

 glycosuria ; alimentary, transitoi*y, and intermittent glycosuria ; persistent gly- 

 cosuria — urinary changes, blood and clinical symptoms, pathology and diagno- 

 sis, metabolism, ti"eatment and prognosis; levulosuria, maltosuria, the occur- 

 rence of isomaltose, laiose, heptose, paidose, glycogen, animal gum, and inosit 

 in the urine; lactosuria, galactosuria, saccharosuria, pentosuria, and the occur- 

 rence of glucuronic acid in the urine; alkaptonuria, diabetes insipidus; and the 

 chemical properties and reactions of the carbohydrates and related substances. 



Many bibliographical references are appended. 



Experimental studies in g-lycosuria immunity, F. Lanzaeini (Riv. Clin. 

 Pediatr., 10 {1912), No. 3, pp. 185-203; ahs. in Ztschr. Immunitdtsf. u. Expt. 

 Ther., II, Ref., 6 {1913), No. 15, p. 1057). — By treating a sheep subcutaneously 

 with slowly increasing doses of glucose, it was possible later to give the animal 

 a large amount of glucose without having it appear in the urine. A glucose- 

 splitting ferment is elaborated in the system but the immunity produced is not 

 permanent. The same findings were noted in a goat receiving saccharose but 

 some of the enzyms produced in the blood were noted in the milk. 



On the distribution of potassium in renal cells, C. P. Brown {Trans. 

 Canad. Inst., 9 {1912), III, No. 22, pp. 389-1,07, pis. 2).— "The sodium cobalt 

 hexanitrite reagent (CoNa3(N02)B+nH20), as prepared by Professor Macallum, 

 is a suitable reagent for the localization of potassium in kidney tissue. It is 

 essential that the tissue be frozen while perfectly fresh, and that the sections 

 prepared from it be kept frozen until they come in contact with the reagent. 

 There is a definite localization of potassium on the external surface of the con- 

 voluted tubules and frequently about their lumina as well. The uniformity of 

 this localization about the tubules tends to increase in direct proportion to the 

 state of activity of the kidney. In the resting condition or during ordinary 

 activity the only potassium demonstrable in the cytoplasm of the cells of the 

 convoluted tubules is condensed in a layer immediately adjacent to the lumen 

 border in each cell. This localization appears to be in accordance with surface 

 tension phenomena. 



" The presence of potassium in the lumina of the tubules and absence of 

 potassium in the glomerular cavity is evidence that the inorganic salts are 

 excreted by the tubule cells. No evidence bearing on the manner in which the 

 glomeruli perform their function was obtained. In no instance was any potas- 

 sium found in a cell nucleus. The amount of potassium in the kidney of the 

 dog and even of the frog exceeds that of the sodium, and in the dog it exceeds 

 greatly the amount of potassium in the blood or plasma," 



The toxicity of gentian violet and its fate in the animal body, J. W. 

 Churchman and L. F. Herz {Jour. Expt. Med., IS {1913), No. 5, pp. 579-583, 

 pis. 2). — Observations of the bactericidal properties possessed by gentian 

 violet, and particularly of its affinity for pyogenic organisms, led the authors to 

 attempt to determine the toxicity of this substance and its fate in the animal 

 body. They here report upon a series of some 75 experiments made on dogs 

 and rabbits. 



