VETEBINAKY MEDICINE. 281 



62 per cent, and when the test was made in combination with the ophthalmic 

 reaction, 78 per cent of the cases were detected. 



For the post-mortem detection of the disease the test will probably prove 

 positive each time that the organs are utilized for making the extracts. 



About the preparation of bacillary extracts for complement fixation, W. 

 Pfeileb and G. Weber {ZAschr. Immunitdtsf. u. Expt. Ther., /, Orig., 15 {1912), 

 No. 2-S, pp. 180-185; abs. in Centhl. Bakt. [etc.], 1. Abt., Ref., 56 (1913), No. 12, 

 p. S59). — It was found that repeated shaking of the glanders bacillus suspen- 

 sions in preparing extracts was unnecessary. It is sufficient simply to cen- 

 trifuge the suspension and to utilize the uppermost clear fluid for the tests. 

 Bacillary suspensions could be boiled without affecting their activity. An 

 analogous finding was noted with the hog cholera bacillus and other micro- 

 organisms. 



Malta fever: Cases occurring in Arizona, C. E. Yount and R. N. Looney 

 {Aru. Med. Jour., 1 (1918), No. ^, pp. 18-27; abs. in Jour. Amer. Med. Assoc, 

 60 (1913), No. 22, p. 17JfO). — A description of 5 cases of malta fever in man, as 

 previously noted (E. S. R., 27, p. 8S4). 



Malta fever in Louisiana, C. Wellman, A. Eustis, and S. S. Schochet 

 (Amer. Jour. Trop. Diseases and Prev. Med., 1 {1913), No. 5, pp. 393-896, fig. 

 1). — The authors report upon a case of Malta fever in a man, detected at New 

 Orleans by means of the agglutination tests, who evidently became infected in 

 Jackson County, Texas. 



Immunizing tests against rabies, H. Miessneb, Kliem, and Kapfbergee 

 {Arch. Wiss. u. Prakt. Tierlieilk., 39 {1913), No. 3, pp. 169-209; abs. in Berlin. 

 Tierdrztl. Wchtischr., 29 {1913), No. 21, p. 386). — The pui-pose of the work was 

 to devise a method for immunizing domesticated animals against rabies. The 

 various methods used for man are based on the principle that small doses of 

 attenuated fixed virus are necessary to bring about immunity. In these experi- 

 ments it was found that with 3 intravenous injections of fixed virus it was 

 possible to produce an immunity, providing the control infection of the animal 

 was allowed to follow some weeks later. The formation of immune bodies pro- 

 ceeds slowly. For the dog the intra-abdominal route is preferred. The curative 

 treatment occupies a secondary position. It is ad\isable to immunize all ani- 

 mals (dogs) yearly. 



The tests for preparing a highly potent immune serum for all classes of ani- 

 mals have not been completed. Tests with salvarsan against this disease were 

 conducted but with negative results. The detection of Negri bodies in rabbits 

 used for the transference (passage) experiments with fixed virus was success- 

 ful in 80 per cent of the cases. The transference of vims from mother to fetus 

 was also noted. Three animals (1 sheep and 2 rabbits) infected with street 

 (passage) virus became rabid in 2 days. The aqueous and vitreous humor of 

 rabid rabbits' eyes can produce typical rabies when injected into other rabbits. 



New immunizing tests in rabies, W. Pfeileb {Berlin. Tierdrztl. Wchnschr., 

 29 {1913), Nos. Ut, pp. 249-252; 15, pp. 269-273). — After giving a description of 

 the research work which led up to the discovery of the antirabic vaccination 

 and the details ot the various modifications of Pasteur's method, attention is 

 called to the value of immunizing domesticated animals against rabies. The 

 number of tests thus far conducted Is regarded as inadequate to properly judge 

 the efficiency and practical utility of immunization. 



The results of tests conducted at the Emperor William Institute of Agricul- 

 ture at Bromberg by Miessner, Kliem, and Kapfberger are discussed in the 

 article. All animals, with the exception of those from which it was desired to 

 obtain an immune serum, were immunized by the rapid method. Some of the 

 tests seemed satisfactory while others were entirely discouraging. 



