766 EXPERIMENT STATION RECORD. 



the values for urinary indican and fecal bacteria nitrogen under all conditions. 

 A definite relationship would probably be accidental." 



Studies on water drinking. — XVI, The influence of distilled water drink- 

 ing- with meals upon fat and carbohydrate utilization, N. R. Blatherwick 

 and P. B. Hawk (Jour. Amer. Chem. Soc, S6 {191 J^), No. 1, pp. 152-157). — Two 

 Bubjects, young men, were maintained upon a uniform diet, and the effect was 

 noted of the copious ingestion of distilled water with meals upon the utilization 

 of the ingested fat and carbohydrate. "The utilization of these nutrients was 

 apparently uninfluenced by the drinking of large volumes of water at meal 

 time." 



Studies on water drinking. — XVH, The ammonia output as an index of 

 the stimulation of gastric secretion following water ingestion, F. Wplls and 

 P. B. Hawk (Jour. Amer. Chem. Soc, S6 (lOllf), No. 1, pp. 158-165). — In 

 experiments with 2 men It was found that the ingestion of water at meal time 

 was accompanied by an increase In the renal excretion of ammonia, directly 

 proportional to the extra volume of water ingested. 



" Inasmuch as certain experiments have demonstrated that water stimulates 

 the flow of an acid gastric juice and as certain other experiments have demon- 

 strated that the formation of acid in the body or the introduction of acid from 

 without produces an increase in the urinary ammonia excretion, we feel justi- 

 fied in assuming that the increase in the ammonia excretion observed in our 

 experiments was due directly to the stimulation of gastric secretion by the 

 Ingested water. 



" The imiform relationship between the water ingestion and the ammonia out- 

 put might perhaps be considered as indicating that there was an attempt on the 

 part of the gastric cells to maintain a uniform acid concentration." 



Calculated on the basis of 100 cc. increasing water ingestion, the increased 

 ammonia excretion was found to be a trifle higher during moderate than during 

 copious water drinking. Indicating that after a certain limit in water ingestion 

 is reached the water was less eflicient as a stimulating factor in ammonia excre- 

 tion. That different organisms may respond differently to Identical stimuli was 

 Indicated by the fact that the ammonia output of one subject was 100 per cent 

 greater than that of the other under uniform conditions. 



" That the increase in the ammonia excretion did not arise from intestinal 

 putrefaction was indicated by the finding of lowered indican values during the 

 period of high water ingestion." 



Concerning the proteins of muscle juice, F. Bottazzi (Rend. Soc. Cliim. 

 Ital., 2. ser., 5 (WIS), No. 11, pp. 282-285) .—Technical studies are here reported 

 with two proteins obtained from the expressed juice of different types of mus- 

 cular tissue. One, found in solution, is named by the author myoprotein. For 

 the other, held in suspension in the form of minute granules, he retains th-e 

 classic term myosin. From 35 to 45 per cent, or even more, of the total protein 

 of muscles was found to consist of these two forms. The viscosity, surface ten- 

 sion, and imbibition of the granular preparatione were tested. 



The extractives of muscle — creatosin, a new base of meat extract, R. 

 Krimbebg and L. Izrailsky (Hoppe-Seyler's Ztschr. Physiol. Chem., 8S (19 IS), 

 No. If, pp. S24-SS0). — The authors have isolated two previously unknown bases 

 from meat extract. One of these, to which the name creatosin has been given, 

 has, in combination with the gold from auric chlorid used In Its separation, the 

 formula CnHMNsOtAuiCl*. Its detailed characteristics and those of the other, as 

 yet unnamed base, are to be studied further. 



Studies in the heat production associated with muscular work, J. S. Mac- 

 DONALD (Proc. Roy. Soc. [London], ser. B, 87 (191S), No. B 59S, pp. 96-112, pi. 



