578 EXPERIMENT STATION EECOED. 



of which three are described as new, and five species of Ciliata. A bibliog- 

 raphy of 69 titles is apppeuded. 



A note on the transmission of spirochetes, J. L. Todd {Proc. Soc. Expt. 

 Biol, and Med., 10 {1913), No. 4, pp. 134, 135).— The author finds that the 

 coxal fluid of Oniithodoros mouhata Infected with Spirochwta duttoni, even 

 when free from anal excretion, contains spirochetes. 



About the isolated active substances of the hypophysis, H. FtJHNER (Deut. 

 Med. Wchnschr., 39 {1913), No. 11, pp. 491-493, pi. i).— From the pituitary 

 bodj' a pure crystalline material (composed of 4 substances) was isolated, 

 which is capable of reducing and increasing the blood pressure and stimulating 

 the contraction of the uterus. The name " Hy]jophysin " has been given to the 

 substance which has all the properties of pituitary body extracts. 



Deviation of complement with melitensis and paramelitensis, L. N^gre and 

 M. Raynaud {Compt. Rend. Soc. Biol. [Paris], 14 {1913), No. 20, pp. 1115, 

 1176). — While the serum of an animal Immunized against Micrococcus 

 melitensis will deviate with a paramelitensis antigen, it will deviate to a 

 greater extent with the homologous antigen. On the other hand the parameli- 

 tensis serum deviates the same amount of complement with melitensis antigen 

 as it does with paramelitensis antigen, consequently the complement fixation 

 test can not be relied upon as a method for diagnosing Malta fever. 



Specific therapy of contagious vaginal catarrh with local immunizing 

 Bubstances, K. v. Sande {Berlin. Tierdrztl. Wchnschr., 29 {1913), No. 20, pp. 

 365, 366). — A description of colpitol, or an immunizing substance prepared from 

 the streptococcus causing colpitis granulosa, and claimed to have given satis- 

 factory results (E. S. R., 27, p. 886). 



The present status of foot-and-mouth disease in Germany, O. Knispel 

 {Mitt. Deut. Landw. GeselL, 28 {1913), No. 52, pp. 699-701).— This discussion 

 includes a table which shows the occurrence of foot-and-mouth disease in the 

 29 Provinces of Germany and in other European countries during the first 11 

 months of 1913. 



Immunization tests with glanders vaccine, J. R. Mohler and A. Eichhorn 

 {Amer. Jour. Yet. Med., 8 {1013), No. 12, pp. 641-649; Amer. Vet. Rev., 4^ 

 {1913), No. 1, pp. 31-46). — This investigation was made with guinea pigs and 

 horses and a vaccine prepared by the New York City Board of Health labora- 

 tory which consists of a suspension containing 2 mg. of dried glanders bacilli 

 to the centimeter. The horses, 17 in number, were purchased in the open mar- 

 ket : they were aged but otherwise in fair condition and were subjected to the 

 agglutination, complement fixation, and ophthalmic mallein tests previous to 

 vaccination. The animals were kept in corrals and after vaccination were 

 exposed to 2 animals which were artificially infected with the glanders organ- 

 ism. All of the animals were subjected periodically to a clinical examination. 



In order to note whether any of the vaccinated animals were infected with 

 the latent form of the disease, they were tested by the ophthalmic method. 

 The method gave surprising results inasmuch as 2 of the vaccinated horses 

 yielded a marked reaction. The glandered horses to which the animals were 

 exposed also reacted strongly, as did also one of 2 check animals held in the 

 corral for control purposes. One month later the animals reacted again but 

 not quite so intensely. The 2 vaccinated horses and the check horse, when 

 killed some months later, were found to have pulmonary glanders. 



During the process of immunization the blood of all the horses was submit- 

 ted to the agglutination and complement fixation tests. " It was found that 

 the agglutination value of the serum of the vaccinated horses, as a rule, in- 

 creased from the third day after the first vaccination and continued to rise for 



