282 EXPEEIMENT STATION EECOKD. 



Biochem. u. Biophys., 10 {1910), No. 4, P- 183). — The so-called antitrypsin which 

 occurs in urine and blood serum is not a specific body but a complex of colloidal 

 active substances. In experimental nephritis an excess of antitrypsin is ex- 

 creted. Serum antitrypsin was not increased by immunizing tests, but on the 

 other hand, an increase was noted when the ureters were tied or the kidneys 

 extirpated. 



Investigation in regard to the bactericidal power of the leucocytes, C. A. 

 Klino (Ztschr. Imimntitatsf. u. Expt. Thcr.. 1. OrUj.. 7 {1910). No. 1-2, pp. 1-93, 

 pi. 1). — By heating polymorphonuclear leucocytes for one-half hour at 50° C. 

 in bouillon, at 37 to 38° in dilute hydrochloric acid or sodium hydrate, or by 

 repeated freezing and thawing, the endolysins are extracted from the proto- 

 plasma. Endolysins destructive to the Bacillus subtilis or typhosus could not 

 be obtained by digesting in bouillon, salt solution, or in 5 per cent inactivated 

 serum for one-half hour at 37°. The extract of polymorphonuclear leucocytes 

 from rabbits, guinea pigs, and cats was capable of destroying the timothy hay 

 bacillus, the grass bacillus II. Koni's acid-fast bacillus I, and Rubner's butter 

 bacillus. Rabbit leucocyte extracts behave in a like manner toward the 

 tubercle bacillus Arloing and the human type of tubercle bacillus. The living 

 polymorphonuclear leucocytes do not when inoculated into the guinea pig lessen 

 the virulency of the human tubercle bacillus. 



Serotherapy, seroprophylaxis, and vaccination against foot-and-mouth dis- 

 ease, and their value for the veterinary inspector, F. Loeffler {Deut. Med. 

 Wchnschr., 35 {1909), No. 48, pp. 2097-2101; abs. in Hyg. Rundschau, 20 

 {1910), No. 15, pp. S.'fO, 841). — A report read at the International Veterinary 

 Congress held at the Hague in 1909, which deals with the progress made in 

 combating foot-and-mouth disease among hogs, calves, and sheep during the last 

 few years. The value of the immunizing serum is discussed. 



Hypo- and histo-eosinophilia in foot-and-mouth disease, G. Vallillo {Clin. 

 Vet. [Milan], Scz. ScL, 33 {1910), No. 1-3, pp. 1-9; ahs. in Berlin, Tiemrztl. 

 Wchnschr., 26 {1910), No. 34, p. 671). — The author determined that in the ex- 

 anthematous stage of foot-and-mouth disease a hypoeosinophilia took place, 

 while in the areas of the body where the disease is localized or where the virus 

 is discharged without any visible lesions (rennet stomach and intestines) a 

 hypereosinophilia is present. 



Diagnosis of glanders with the complement binding method, J. de Haan 

 {Berlin. Tierarzil. Wchnschr., 26 {1910), No. 32, pp. 6,93-638).— This is a study 

 of the circulation of antibodies in the blood serum of glandered horses in Java. 



The author shows on the basis of his tests, bacteriological examinations, and 

 autopsies that the examination of the serum for antibodies has almost the same 

 value as the mallein test, but considers that when a negative antibody reaction 

 is obtained and a positive mallein reaction the benefit of the doubt is to be given 

 the mallein test. 



The treatment of suppurative conditions in animals by bacterial vaccines, 

 including a preliminary report of the use of a hyperimmune serum in canine 

 distemper, J. I\I. Phillips {Amer. Vet. Rev., 36 {1910), No. 6, pp. 656-671).— 

 The author describes his (and McCampbell's) method for preparing autogenous 

 bacterial vaccines. This consists of making 24-hour cultures on agar slopes of 

 the material taken directly from lesions and then suspending the growth in a 

 0.85 per cent sodium chlorid solution preserved with 0.5 per cent carbolic acid. 

 The author makes use of McFarland's nephelometer ^ for obtaining the pi-oper 

 dilution of the bacteria. 



ojour. Amer. :^Ied. Assoc, 49 (1907), pp. 1176-1178. 



