388 EXPERIMENT STATION RECORD. 



In Germany the method which for the time is receiving most attention is 

 that proposed by Ostertag. This consists in eliminating by slaughter all 

 clinical cases of tuberculosis, removing the calves promptly after birth from 

 their dams and keeping them separated for some months, after which they may 

 be placed with the other cattle. 



Although there is no country where the feeling is stronger that bovine tuber- 

 culosis is of great sanitary significance than Great Britain, there seems to be 

 no other where so little direct effort has been put forth to eliminate this disease 

 from cattle. In Holland at present only cattle belonging to breeders are killed 

 and compensated for by the government. 



" The lesson from the experience in Denmark is that in order to keep herds 

 free from tuberculosis the owner must be educated in the nature of the disease 

 and that until he is thus educated there is little hope of securing herds per- 

 manently free from this disease." 



A new tuberculin, F. J. Rosenbach {Dciit. Med. Wchnschr., 36 (1910), Nos. 

 S3, pp. 1513-1517; 3-'t, pp. 1553-1551 ; ahs. in Schioeiz. Wchnschr. Chem. u. 

 Pharm., 48 {1910), No. .',1, pp. 637, 638).— The tuberculin is produced as follows: 



A few particles of the fungus Trichophyton holosericum album are sprinkled 

 on a G to 8-week old tubercle bacillus culture and allowed to develop for from 

 10 to 12 days at from 20 to 22° C, or until the greater part of the culture is 

 covered with the myceliiB of the fungus. After this the culture mass (tubei*cle 

 bacilli and mold fungus) is separated from the liquid, rubbed up with a 

 glycerin-carbolic-acid solution, and filtered. The filtrate is then mixed with 

 the original culture solution filtrate, made up to 10 times the bulk of the 

 original fungus mass (tubercle bacillus-ftrichophyton), and conserved with a 

 1/2 per cent carbolic acid solution. The tuberculin is given in doses for man of 

 from 0.01 to 0.1 and 0.2 gm., whereas the old tuberculin of Koch takes for its 

 initial dosage from 0.001 to 0.01 mg. 



Comparisons are made between this tuberculin and others. 



Investigations in regard to bacillary pseudotubercular diseases, with par- 

 ticular regard to pseudotuberculosis ovis, K. Glassek (Arcli. Wiss. u. Prakt. 

 Tierheilk., 35 (1909), Nos. i,-5, pp. J,71-510; 6, pp. 582-613, pis. 2, flgs. 2; ahs. 

 in Berlin. Tierdrstl. Wclmschr., 26 (1910), No. 34, p. 671).— As a result of his 

 work the author concludes that only one pseudotuberculosis bacillus exists, 

 but that this appears in numerous varieties which he classifies as follows : 

 One specially pathogenic to mice (Bacillus pseudotuberculosis murium), one 

 variety pathogenic for mice and rats (Sabrazis var.), one which is pathogenic 

 to the remaining gnawing animals (B. pseudotuberculosis rodentium), and one 

 which is pathogenic for sheep (B. pseudotuberculosis ovis). 



In the sheep the pathological processes with this bacterium are entirely 

 different from those of true tuberculosis, so that the term " Pseudotuberculosis 

 ovis " is not well selected. On the other hand, a close relation seems to exist 

 between this disease and Pyohacillosis bovis and P. suis, as in both conditions 

 the pathological and anatomical processes have some features which are 

 identical (such as pus formation). The moi'phology, staining, and cultural 

 characteristics of the two causative bacteria also agree very well. 



Epizootic abortion in cattle, J. Mc Fad yean et al. (Rpt. Dept. Com. Bd. Agr. 

 and Fisheries {Gt. Brit.^, Epizootic Abortion, 1910, pt. 2, pp. 118). — The greater 

 part of this second paper (E. S. R., 22, p. 584) is taken up by the minutes 

 of evidence submitted by the principal societies representative of cattle breed- 

 ing and dairying in Great Britain, a total of 18 witnesses having been ex- 

 amined. 



The evidence thus gained is briefly reviewed by the committee who recom- 

 mend that as a preliminary measure this affection be dealt with by compulsory 



