84 EXPERIMENT STATION RECORD. 



bo oxpl.-iiiicd liy tli<' trrcat dilutinn in wliicli llic liilc exists in the body of the ex- 

 l»eriiiieiit:il aniniai. 



Action of the component elements of the bile on tetanus toxin, H. Vincent 

 {('oiHiit. liiiid. Soc. liiol. \l'<inx\. (i.S (I'.Wl), No. 37, pii. ()!)'>-()97). — In con- 

 tintialidii of (lie work noted above, it appearetl desirable to determine the par- 

 ticular elenients of tlie l)ile upon which its antiseptic property depends. A study 

 of this problem showed that all of the essential elements of the bile possess an 

 antiloxic ))owi'r toward tetanus toxin. Tlie antitoxic jiroperty of cholesterin 

 is somewhat firealer than that of lecithin and bile salts. 



Experiments in the use of epsom salts in the treatment of tetanus, 1j. 

 ("KrvKiLiiiKK (Coiiiiit. Rend. .Sw. Biol. \r(iris], 67/ (1908), No. 3, iip. 111-1J3).— 

 Several investijralors h.ive sujigested the use of epsom salts in treating tetanus. 

 'Phis drug was tested by the author who administered it hyiKtdermically to 

 mice ;ind guinea pigs in a 2 per cent solution. No benettcial results were ob- 

 tained and the .-luthor concludes that in the treatment of this disease no de- 

 pendence should be i)laced upon epsom salts. 



Inoculation tuberculosis in cold-blooded animals, G. Moriya {Vciithl. lidkf. 

 [ctc.l, J. AM., Grig., .',5 {1007), No. .',, iip. 2!>-',-301, 1>1. J).— In a series of inocu- 

 lation experiments the author found that human tubercle bacilli were by uo 

 means easily modified into the form of tubercle bacillus usually found in cold- 

 blooded animals. The author believes that before such transformation can be 

 assumed to be possible it is necessary that further careful experiments be 

 carried out on this line. 



Fetal tuberculosis in calves, II. L. Ellerman and H. C. DeWaal {Tijdsclir. 

 Vccaii.sniijl-., 3'i {1908). No. '/, /</>. .112-117). — A detailed description is given 

 of the tuberculous lesions observed in a pregnant cow. The disease liad become 

 generally distributed throughout the organs of the body and had affected the 

 uterine cotyledims, from which pure cultures of tubercle bacilli were obtained. 

 From these points the infection had spread to the fetus, causing characteristic 

 lesions in various lymphatic glands. 



The influence of Avounds on the localization of tuberculosis, A. Rodet and 

 Jeaniirau {Coiiiiit. Rend. Acad. Sci. [I'ari>i\, l.'i'j {1907), No. 2(j, pp. 1361- 

 1363). — It has sometimes ]i<'en assumed that tubercle bacilli possess a ten- 

 dency to become localized in wounds which exist at the time of infection or 

 arise subsequently. The author's experiments on rabbits led to negative re- 

 sults in this regard. Tubercle bacilli introduced through the alimentary tract 

 led to distinct lesions in the lungs, but did not produce any subsequent lesion 

 in artificial wounds in tlie joints. 



The action of chlorin on the tubercle bacillus, (i. Moussu and (Joupil 

 {Vompi. Rend. Acad. Sci. [Paris], t.',5 {1907), No. 2.'i, pp. 1231, 1232).^ln the 

 opinion of the author it has been shown that the acid-resisting property of tlie 

 tubercle bacillus depends not alone upon its content f)f fatty substances, but 

 also upon its i)rotoplasm and other chemical constituents. The author found 

 that if cultures of tubercle bacilli be subjected to the action of chlorin fumes 

 the acid-resisting power of the bacilli disappears rapidly. 



The formation of antibodies from the substance of the tubercle, E. Ber- 

 tarelli {Ccnthl. Bakt. [etc.], 1. Aht., Grig., J,.5 {1907), No. 1, pp. 6.2-67).— Dur- 

 ing the development of the tubercle in susceptible animals the process is not 

 confined to alterations of the ti.ssues as a consequence of necrosis or other 

 pathological changes, but under the influence of the bacterial invasion molecular 

 combinations occur which result in new bodies previously not to be found either 

 in bacterial cultures or in the tissue of the animal organism. These antibodies 

 may possibly prove of some service in the production of immunity. 



