VETERINARY MEDICINE. 



683 



months following tho socoiul vacrination with tho results shown in tho following 

 lahio: 



Ifr.sults of fiilicrciilin tisfs ntailc upon racrinntcd and control dnimali^. 



Date tested. 



May, 1906 



November, 1906 

 Januarv. 1907 .. 



April, 1907 



October, 1907 . . 

 January, 1908.. 



At a post-niortoni oxaniination niado in May, 1007, lesions wore found in 8 

 different lymphatic jrl.mds and the pleura of 2 of 5 control animals ex- 

 amined. It appears probal)le that the immunization process sensitizes the 

 animal for a time so that it is more susceptible to tuberculosis than at first. 

 -Vfter a time this condition of sensitization disappears and the body acquires 

 increased powers of resistance. Post-mortem examinations of 4 of the vac- 

 cinatetl animals that had given apparent reactions at least twice resulted 

 in the finding of typical more or less extensive tubercular lesions. From the 

 fact that but one reacted within a year after the completion of the vaccination 

 it is concluded that the infection was acquired subsequent to the completion of 

 the imnnmizing process. 



The authors conclude that while vaccination materially increases the resist- 

 ance of most aninjals it does not do so in all cases. Considering the expense 

 of the i)rocess, the time required, the fact that only young stock can be treated 

 and that they must be separated from all sources of infection during the 

 inununizing process, and that a certain percentage of the vaccinated animals 

 will ac(|uire infection in sjnte of the treatment, the practicability of the method 

 is considered do\il)tful. The experiments have not been continued a sufficient 

 period of time to determine the permanence of the immunity produced, but 

 European investigators are said to have found that the immunity induced dis- 

 ai)|»eare(l within a year or two after the vaccination. The authors do not con- 

 sider tlie system in its present stage of development as one to be recommended 

 lo the farmers of the State. 



Persistence of tuberculin in the body of the goat. A. Slatineano and C. 

 .loNKsco-.MiiiAiKSTi (Compt. h'cnd. Soc. Biol. [I'ari.sl, Oj (1908), No. .9, /). .'(20). 

 -Tuberculin was foiuid in the blood of a goat 12 days and in the urine IS 

 days after the inject ion of 10 cc. into tiie veins. 



Osteoporosis in animals, II. Inci.k (Transriial Drpt. A[/i: Ann. h'pt. 1905-6, 

 pp. 19H-207). — Hones from diseased and healthy mules, horses, and donkeys 

 were analyzed, and the following conclusions drawn: "(1) That in animals free 

 from disi'ase, the bones contain larger proportions of total ash, lime, and 

 p!iosi)horic acid than are to be found in the bones of animals suffering from 

 the diseas(;; and (2) that the ratio of nitrogen to ash in the bones furnishes 

 perhaps the easiest and most direct method of judging of the freedom or 

 otherwise of tt'.e animal from osteoporosis." Rones of diseastnl animals also 

 apiM'ared to contain more silica tijan tho.^e of healthy anim.ils. 



As a result <tf his investigation the author believes that the abnormal cim- 

 dition of the Ixtnes is Induced by the use of foods not necessarily deficient in 

 lime nii<l phosphates, but in which the ratio of lime (and p«'rhaps magnesia) 



