VETERINARY MEDICINE. 881 



tuberculin gave a positive reaction. The author considers the cervical vertebra 

 to be a vi>ry coiuuu)n seat of tuberculosis in the horse. 



Tuberculosis affecting the dorsal vertebra of a mare, W. Krown ( Vet. Rec, 

 21 (1!)()S), /Yo. 1052, 1)1). l.'io, I'll}, fltjH. 2).— A case of this affe'ction is reported 

 iicconipanied by photographs. 



Control of hog cholera by serum immunization, A. D. Mklvin {Amcr. ^'et. 

 Ra:. S.'f (/.WN), Xo. 1, pp. l.',-21).—lu this article, which was presented before 

 the annual meeting of the American \eterinary Medical Association, an account 

 is jiiven of the methods of ininumi/ation that have been w<n-ked out by the 

 biocheniic division of the Bureau of Animal Industry of this Department and 

 which have been patented in such manner as to insure to the people of the 

 United States the right to a free use. 



Up to the in-esent time the filterable virus causing hog cholera has not been 

 artificially cultivated. A protective serum is produced by hyperinnnunization. 

 With a standard serum of known potency susceptible pigs may be protected in 

 two ways, by the so-called serum-sinniltaneous method and by the serum-alone 

 method. The former, to be used in droves that have not been exposed to hog 

 cholera, consists of injecting subcutaneously on one side of the body of the pig 

 to be vaccinated a suitable quantity of serum and simultaneously on the other 

 side of the b(jdy a small quantity of virulent blood taken from a hog sick with 

 hog cholera. p]xperiments have shown that pigs are thereby given a firm 

 immunity lasting at least 6 months and probably much longer. The serum-alone 

 niethcxl which consists simply in injecting the protective serum appears to 

 confer only a temi>orary immunity upon the treated pigs. This latter methcxl 

 is adapted to the treatment of hogs in a herd in which cholera has already 

 l)roken out but which have not themselves shown visible symptoms of the 

 disease. It is estimated that the cost of the serum per dose can be brought to 

 25 cts., as there seems to be no objection to the use for food purposes of the 

 carcass of a hyperimmunized immune. 



Experiments have been carried out upon farms under practical conditions. 

 Some 2,(X)0 hogs on r>0 farms were thus treated during the fall of 1907 and the 

 results show the efficiency of the method. The practical use is considered 

 entirely feasible. Plans for the eradication of hog cholera by serum immuniza- 

 tion are submitted. 



Inoculation against hog cholera, J. W. Connaway { Breeder's Qaz., 53 

 ( IHOS), .\o. 20, i>p. 1105-1101, pijs.. 7). — P^xperiments conducted by the author in 

 which virulent hog-cholera blood and hyperimmune serum were injected sinml- 

 taneously are here reported. Out of 50 head that apiieared healthy at the 

 time of inoculation only 3 died. All of these are said to have been exposed as 

 nuich as would ordinarily occur on the average stock farm. The injection of 

 serum into sick hogs did not appear to modify the course of the disease. 



Studies on hog cholera and preventive treatment, \V. K. King {Kansas Sta. 

 Jiul. 157, pp. .n-'.io, pis. s. ih/iiis. .}',). — The investigations here rejKirted were 

 conducted in cooperation with Dr. C. T. McClintock, following unsuccessful 

 attempts to attenuate virulent hog-cholera blood by various physical and chem- 

 ical means. 



Negative results were obtained from attempts made to cultivate the filter- 

 able virus of hog cholera artificially in normal hog-serum broth in the abdom- 

 inal cavity of the rabbit in c<»llodiinn saes. 



As a large (piantity of innmnie serum is requin-d in the ordinary preventive 

 treatment and sinc(^ relatively small amounts are secured from individual 

 hogs, experiments were made with other animals in view of producing a serum 



