1184 EXPKIUMKNT STATION EECOKD. 



Ikt at tlip boginniiifx of (lir oljscrvatioii, hut on the thinl day luort' than 1.ir>2 

 were present in each speek deiiosited. Only one bacilhis was found between 

 the third and sixth day and tlie acid-proof bacilli were not infective when 

 injected into the subcutaneous tissue of a Kni'iea pif^." 



The etiology and diagnosis of hydrophobia, Anna W. Williams and May 

 M. LowiJioN {Ann. Rpf. Ih/it. Ilcdlth Citij of S'cir York, I'.IOd, vol. .i, />/>. 6'JJ- 

 6"77). — Some of the conclusions drawn by the autliors following the investigation 

 here reported are : 



"The smear method of examiniui; the Neiiri bodies is superior to any other 

 method so far published. . . . 



"The Negri bodies as shown by the smears as well as b\- llie sectious are 

 specific to hydrophobia. 



"Numerous ' bodii'S ' are found In lixed virus. ' Uodies ' are found before 

 the beginning of visible symptoms — i. e., on the fourth day in fixed virus, on 

 the seventli day in street virus, and evidence is given that they may be found 

 early enough to account for the appearance of infectivity in the host tissues. 

 Forms similar in structure and staining (jualities to the others, but just within 

 the limits of visible structure at 1,500 diameter magnification have been seen. 

 Such tiny forms, considering the evidence they give of plasticity, might be able 

 to pass the coarser Berkefeld filters. 



" The Negri bodies are organisms belonging to the class Protozoa. The rea- 

 sons for this conclusion are: (a) They have a definite characteristic morphol-. 

 ogy; (b) this morphology is constantly cyclic, i. e., certain forms always 

 predominate in certain stages of the disease, and a definite series of forms 

 indicating growth and multiplication can be demonstrated; (c) the structui'o 

 and staining qualities as shown especially by the smear method of examination 

 resemble that of certain known Protozoa, notably of those belonging to the 

 suborder ]\licrosporidia. The proof that the ' Negri bodies ' are living organisms 

 is sufficient proof that they are the cause of hydrophobia." 



The prevalence of hydrophobia in the Philippine Islands, F. W. Dudlky 

 (Jour. Amcr. Mcil. Assoc, 51 (lOOS), Xo. .io, vi). 2L',S-21.','J).—ln response to 

 circulars mailed by the author, cases which largely occurred between October 

 1, 1902, and February 2S, 1907, were reported as follows: In 253 dogs, 3 cats, 

 1 carabao, 1 cow, 4 horses, 2 pigs, 3 rats, and 1 monkey. Thirty-nine provinces 

 were shown to have been infected by the disease, 10 having escaped according 

 to reports. The author considers the disease sufficiently prevalent to warrant 

 the (Jovernment in i>roviding means for the Pasteur treatment. 



Transmission of rabies to mice by ingestion, I'. Kkmlinokr (Co)iu>t. Jirnd. 

 Hoc. Biol. [Parish, 65 (i^ON), No. 30, pp. 385, 3S6').— Experiments indicate that 

 mice can contract rabies not only when bit by an affected dog or cat but also 

 when they eat virulent parts of an animal dead from the disease. 



Experiments on the production of antirabic serum, D. W. Poor and P. J. 

 Friedaean {A)ih. Rpt. Drpt. Hnilth Citij of New York, 1906, vol. 2, pp. 682- 

 G!)2). — The following ctmclusions have been drawn from the experiments 

 reported : 



" It is possible to produce a strong innnuiuv serum against rabic virus, in 

 rabbits, sheep, dogs, and horses. 



"For the production of such a serum a long course of treatment is necessary. 



" This serum when fi*esh prolongs the incul)ation of rabies when injected into 

 test animals a short time after infection." 



Note on the investigation of cattle disease in the Protectorate of Sierra 

 Leone, F. IIakvey (Join: Hoy. A Din/ MnJ. Corps, 10 (1908), No. 1, pp. .'/l-'i'i, 

 map 1; 'tbs. ill- Btil. Inst. I'dstciir, G (1908). Xo. 19, p. 883). — An account of a 

 trypanosomiasis that is apparently fatal to cattle, horses, dogs, goats, and prob- 



