VETERINARY SCIENCE AND PRACTICE. 89 



permanganate and aluminum t<ulphate is reoom mended. Special notes are given on 

 wild parsnip, deathcamas, s})eeies <>t hi'^kspur, lupines, and Veralrmn rolifoDiicxm. 



Results of treating- tetanus by inoculation with cerebral emulsion, J. Fie- 

 BKiER {Ztschr. Thiermed., 6 [1902), No. 3, pp. 161-170).— The author found that the 

 rate of mortality from tetanus could be nmch reduced by treatment with cereljral 

 emulsion. The results of this treatment appeared to be quite as satisfactory as those 

 of other known treatments. A treatment, with cerebral emulsion is cheaper than 

 serum therapy and the material is more easily obtained. The technique is not too 

 oom}>licated for the ordinary practicing veterinarian. 



Fixation of tetanus toxin by the brain, Besredka (Aim. In.^t. Pasteur, 17 

 {IDO-i) , Xo. 2, pp. 13S-147). — The literature of this subject is critically discussed. 

 The author made an emulsion of the lirains of guinea pigs, in testing the effect of the 

 brain upon the tetanus toxin. During these experiments it was shown that the 

 cerebral sul)stance is capable of fixing more tetanus toxin than it can neutralize. 

 The fixative substance of the brain is, therefore, not the same as the antitoxic suIj- 

 stance. The cerebral mass, when saturated with tetanus toxin, completely recovers 

 its primitive integrity, after the addition of true antitoxin, whether obtained from 

 an animal of the same or a different species. The combination of the brain sub- 

 stance and the toxin does not give a substance as stable as that obtained by a mixture 

 of toxin and true antitoxin. 



The power of the brain to neutralize tetanus toxin, E. Makx {Ztschr. ILjg. 

 u. InfectionshxinJ:., 40 {1902), Xo. 2, pp. 2S1-2S8). — A brain emulsion was prepared 

 from guinea pigs and experiments wei'e tried in testing the action of this emulsion 

 upon tetanus virus in vitro. The results of these experiments may be stated as fol- 

 lows: The effect of the brain of guinea pigs is united with that of the antitoxin in 

 neutralizing the tetanus toxin in vitro. It is believed, therefore, that the effects of 

 the brain sul)stance and of the antitoxin are functionally of al)oat eifual value. 



Antitetanic properties of the central nervous system of immunized ani- 

 mals, K. Dmitrievski {Ann. Inst. Pasteur, 17 {1903), Xo. 2, pp. 148-160).— The 

 author's experiments were made with the Vjrains of immunized guinea pigs. Strict 

 antiseptic conditions were ol)served in preparing emulsions of the cerebral hemi- 

 spheres, the base of the brain, and the medulla oblongata, without separation of the 

 latter from the upper portion of the spinal cord. Tetanus toxin was mixed with 

 cerebral emulsions thus obtained from the guinea pigs which had received a single 

 injection of tetanus toxin, those which had l:)een immunized for 1 or 2 months, and 

 others which possessed an immunity of 3 or 4 months' duration. The author con- 

 cludes from his experiments that the brain of animals which have enjoyed an immu- 

 nity of short duration, as well as their blood, does not possess any great antitetanic 

 property and does not differ in this respect from the normal brain. The brain and 

 the blood of animals which have been immunized for a long time contains a large 

 quantity of antitoxin and is capable of neutralizing a larger quantity of tetanus toxin 

 than the brain of normal animals. The difference, however, is not very great since 

 all animals which were injected with a mixture of toxin and brain substance from 

 immunized guinea pigs i)resented certain symptoms of tetanus. The blood of animals 

 which have enjoyed a lonsr immunity always contains more antitoxin than the brain. 



The symptoms and prophylaxis of experimental rabies, D. Coxradi {Centhl. 

 Bakt. u. Par., 1. Aht., 33 {1903), Xo. 5, Orhj., pp. 389-.i92) .—The pin-pose of the 

 experiment reported in this paper was to determine the length of the incubation 

 period of rabies under experimental conditions when the inoculation was made as 

 nearly as possiljle in a natural manner. The virus was rul)bed into abrasions of the 

 skin, which were purposely made, so slight that no bleeding took place. The abra- 

 sions thus made and inoculated were washed with solutions of corrosive sublimate 

 after the lapse of from 1 to 10 minutes. During the author's experiments 10 rabbits 

 were treated in this manner, while ?> others were inoculated in the same manner 



