510 EXPERIMENT STATION RECORD. 



Intracerebral injections of various kinds of virus, K. Bkeideut {Fortschr. 

 ]'tl. Hi/'j., 1 {1903), No. 0, pp. 160-167).— I'^xWii^ivG experiments were made, prin- 

 cipally on ral)bits, for the purpose of determining the comparative advantages of 

 making intracerebral injections in the diagnosis of infectious diseases. The organ- 

 isms employed in these experiments included anthrax bacilli, Stupliylocorcus pyogenes 

 aureus, Bacienum avicidum, swine-plague bacteria, and the bacilli of swine erysipelas. 

 The author concludes as a result of these experiments that for the majority of path- 

 ogenic organisms Avhich he has studied the brain substance is a very favorable 

 nutrient medium and intracerebral injection brings about a fatal development of the 

 disease within a shorter time than can l)e accomplished by subcutaneous injection. 

 In the use of the intracerebral method of injection very minute (juantities are suffi- 

 cient to produce results. Cultures may l)e diluted so as to employ one-millionth or 

 even one-billionth cubic centimeter with positive results. The method is therefore 

 recommended in cases where it is necessary to obtain a diagnosis within a very short 

 time. All of the organisms upon which the author experimented were found to 

 develop readily in the brain substance, with the exception of that of swine erysipelas. 



The pyogenic bacteria of cattle, O. Kt^xxE.MANN {Arch. Wiss. u. Prakt. Thierh., 

 '29 {1908), Xo. 1-2, pp. 128-157, fig. l). — The author made elaborate comparative 

 studies for the purpose of determining the relative frequency of various organisms in 

 suppurative processes in cattle. The literature of the subject is critically reviewed. 

 The green-colored multiple abscesses frequently found in the liver of cattle are due 

 to the action of the necrosis bacillus, and this organism can always be found, but 

 sometimes in small numbers. Suppurative pyelonephritis of cattle is characterized 

 by the. constant presence of Bacillus renalis bovis and B. pyelonephritidis bourn in the 

 purulent products and diseased kidney tissue. 



In the pus of the abscesses in cattle, in 90 per cent of cases, the author found a 

 bacillus not hitherto mentioned, which he names B. jjyogenes. It is not identical 

 with a similar bacillus described by Lucet. In 35 per cent of the ca.ses observed by 

 the author this bacillus was found alone in the pus, and in 55 per cent it was asso- 

 ciated with other bacteria. 



The bacterial flora of the intestinal canal of pigs, E. Heixick {Arch. ]yiss. u. 

 Prakt. Tliierli., 29 {1903), No. 3, pp. 476-525). — The author presents in a systematic 

 manner lists of micro-organisms found in the small intestines, cecum, colon, and 

 rectum of pigs. A number of known and unknown species of bacteria were found. 

 Tal)les are given showing the results of inoculation of mice with various organisms 

 found in different parts of the alimentary tract. 



A number of tuberculous hogs were carefully examined for the purpose of deter- 

 mining whether tubercle bacilli were present in the intestines of such animals. No 

 tubercle bacilli could be found, either as a result of microscopic examination or from 

 inoculation of guinea pigs. As a result of the author's investigations, which were 

 made upon 23 pigs, it was found that Bacillus coli conmimiis and B. lactis a'erogenes 

 were the only organisms commonly found in the intestines of pigs. The bacillus of 

 swine erysipelas was not found in a single instance. 



Some experiments on the intravascular use of antiseptics, W. Y. Shaw 

 {Jour. Hyg. [Cambridge'], 3 {1903), Xo. 2, p>p- 159-165). — The author briefly reviews 

 the literature relating to intravascular injection of antiseptics in the treatment of 

 infectious diseases. The antiseptics employed were formalin, guaiacol, and chinosol, 

 and the experimental animals were rabbits. 



Preliminary experiments were made for the purpose of determining the maximum 

 doses of these antiseptics which could be given without causing serious consequences 

 in the experimental animals. The organism with which the rabbits were infected 

 was Bacillus j)yocyaneus. Additional experiments were also made w^ith the tubercle 

 bacillus. The experiments showed conclusively that the course of septicemia pro- 

 duced by B. pjyocyaneus was not checked, but on the contrary was somewhat acceler- 

 ated by the intravenous injection of the antiseptics already mentioned. 



