1120 EXPERIMENT STATloX RECORD. 



A study of chronic infection and subinfection by the colon bacillus, G. A. 



Charlton [Jour, Med. Jiesearcli, 11 {1904), ^o. 2, j>j). 5ii7-'>l!t). — Tlie inoculation 

 experiments reported in this paper were made in raljbits. It was funml tiiat as a 

 result of infection with the coli bacillus a pronounced anemia was j)ro(luci'd, some- 

 what resemljlinj; ])ernicious anemia in man, and accompanied with a great diminu- 

 tion in the number of red blood corpuscles. The disease differs from pernicious 

 anenna, however, in producing a decrease of henioglol)in j)arallel witli the decrease 

 of the red blood corpuscles. In advanced stages of infection a diffuse degeneration 

 of the sjiinal cord was brougiit about affecting chiefly the posterior and lateral col- 

 umns of the cord. 



The action of artificial oxydases on the toxin of tetanus, A. Lu.miere et al. 

 {Compt. Rend. Acad. Sci. Paris, 138 {1904), Xo. 10, jjp. fJ.'>J-^!'>4). — Experiments were 

 carried out during which artificial oxydases composed largely of mineral subf^tances, 

 such as salts of manganese, iron, and cerium were used in testing their effects uj)on 

 tetanus toxin. The samples of the toxin thus treated were later tested l)y the inocu- 

 lation of guinea pigs. It was found that these artificial oxydases, whether of an 

 alkaline or acid reaction, exercise considerable effect upon the toxin of tetanus. 

 The salts of cerium, col)alt, and nickel, as well as those of iron and manganese, 

 attenuate or entirely destroy tetanus toxin. 



Proceedings of the American Veterinary Medical Association for 1903 {St. 

 Paul: Pioneer Press Co., pp. 346, pi. 1, figs. 60). — The fortieth annual meeting of the 

 association was held in the City Hall, Ottawa, Canada, September 1—1, 1903. The 

 papers which were read at these meetings have been previously noted (E. S. R., 15, 

 pp. 112-119). The present published form of the proceedings contains four other 

 papers which were read by title only, together with a list of the members and an 

 account of the business of the sessions. 



Tumors in domesticated animals, J. Desmond {\)]i. 204-212). — In this paper submitted 

 by the government veterinarian of South Australia, an account is given of various 

 tumors of horny and other nature as observed in domesticated animals. Horns on 

 the skin of animals are classified in 4 varieties, viz, sebaceous, wart horns, hoof 

 horns, and cicatricial horns. Notes are also given on tumor-like growths in various 

 organs, esijecially a case of true endothelioma, which is reported as the first case of 

 this sort observed in animals. 



An outbreak of epizootic enceplialitis of tlie horse in South Carolina, G. E. Xesom (pp. 

 213-215). — This disease is said to have prevailed in the South for more than 50 years, 

 being especially severe in the southern Atlantic States. It has been known by a 

 number of common names and has been referred to a number of causes. The author 

 believes, however, that all well-investigated cases are due to eating damaged corn 

 or hay, or sometimes both of these feeds, in a moldy or spoiled condition. 



A question relating to the serum-therapy of the apldha epizootica — its actucd state, E. Per- 

 roncito (pp. 283-291). — The literature relating to this subject is critically reviewed by 

 the author. The results obtained thus far are encouraging but are not quite satis- 

 factory. It is urged that further study should be made of this iirol)lem in order to 

 devise means for the preparation of a more efficient serum in the treatment of foot- 

 and-mouth disease. 



A preliminary report on the sheep disease, ictero-hunnaturia, in Western Montana, II. P. 

 Johnson (i)p. 301-313) . — This disease was observed in Montana in 1890. It is largely 

 confined to Deer Lodge and Silver Bow valleys. The disease is considered as iden- 

 tical with carceag of Europe, and is due to the action of the blood parasite Piroplasma 

 avis. The means of transmission of the disease are not understood. It is suggested 

 that this occurs through the agency of some biting insect, perhaps the sheep tick. 

 Experiments with this insect, however, gave negative results. No success was had 

 in reproducing the disease by means of inoculation with virulent blood. It is sug- 

 gested, therefore, that infection with this disease requires a peculiar susceptibility 

 derived by digestive organs. 



