1124 EXPERIMENT STATION RECORD. 



the amount nf wooil or other fuel necessary for incinerating given weights of ani- 

 mal l)odies. Tlie cost <if destroying the carcasses by this method maybe readily 

 estimated from sncli data. W'iiile it is recognized that this method involves the 

 destruction of niucli valual)U' material, it is considered necessary for the ])resent to 

 incinerate carcasses of animals dead of highly infectious diseases. 



Abridg-ed bibliography of infectious diseases, D. Moxfallet {Bih/ior/rajiJiie 

 Ahrnjre di'-'< JrifcctinnM. Paris and SduiuKjo: ('. <'iifti^ 1903, pp. 65). — In this bil)li- 

 ography the author's purpose was to i)resent for the pracfical investigator and student 

 a list of the most important publications relating to the various infectious diseases (jf 

 animals and man. The numlx-r of diseases on which liibliographies are presented is 

 about 90. 



The principles and conditions of combating" epizootic diseases, ^'. Xagokski 

 Arch. Vet. Nauk, Si. Petersburg, 34 {1904), Xo. 1, pp. 1-2G, Jigs. 7). — A general dis- 

 cussion of the principles involved in eradicating infectious diseases, including an 

 account of quarantine measures, medicinal treatment, disinfection, and preventive 

 vaccination. 



The relations of human and bovine tuberculosis, V. A. Mooke ( Cornell Coun- 

 tryindn, 1 (1904), X<>. 5, pp. 137, 138). — The author outlines in a brief manner the 

 history of the controversy regarding the identity of these 2 forms of tuberculosis. 

 The opinion is maintained that results of investigations indicate conclusively that 

 human and bovine tuberculosis are essentially identical. 



Human and bovine tuberculosis, A. d'Espine {Her. Sci. [Paris], 4. ser., 20 

 {1903), No. 19, pp. .')93-596). — The author reviews briefly the literature bearing on 

 the relationship between these 2 forms of tuberculosis, and concludes that the evi- 

 dence is very strong in favor of their identity. 



Tuberculosis of cattle as related to that of man, E. Pkrroxcito {Extract from 

 Gaz. Mid. It(d., 54 {1903), No. 22, ]>p. 4)- — As a result of the author's experiments 

 and studies of this disease together with a review of the literature of the subject, it is 

 concluded that the human and bovine forms of tuberculosis are essentially the same 

 and are intertransmi.'JsiV)le. 



An inquiry into the primary seat of infection in 500 cases of tuberculosis, 

 J. O. SvMES and T. Fisher {British Med. Jour., 1904, No. 2259, pp. 884, 885).— On 

 account of the importance of determining the extent of infection of man from eating 

 the milk and meat of tuberculous animals, statistics were compiled by the authors 

 relating to 500 fatal cases of tuberculosis in man. From these statistics it appears 

 that, if the local foci of disease are considered as evidence of the primary seat of 

 infection, the percentage of infection during the first 12 years of life is 4 times as 

 great in the air passages as in the alimentary tract. 



The reaction of tuberculous animals to subcutaneous infection •with the 

 tubercle bacilli, F. A. della Cella {Cculbl. Bukl. n. Par., 1. Abl., Orig., 36 {1904), 

 No. 1, pj^. 12, 13). — Experiments were carried out for the purpose of determining 

 what local alterations are caused as a result of subcutaneous inoculation with tubercle 

 bacilli. For this purpose cultures were used which, in moderate doses, caused the 

 death of guinea pigs within a period of 2 weeks. It was found that by greatly reduc- 

 ing the size of the dose the course of infection was much slower. 



In 1 experiment 10 guinea pigs were in(5culated and 20 days after infection were 

 again inoculated subcutaneously with a minute dose of virulent tubercle bacilli. In 

 nontuberculous animals similarly inoculated no local reaction took place until after 

 12 days, while in the tuberculous animals a pronounced local lesion was observed on 

 the day following the inoculation. Similar results obtained in other experiments 

 convinced the author that there existed a sort of local immunity in the subcutaneous 

 connective tissue against tubercle bacilli. This inniiunity is brought about by pre- 

 vious inoculation and is indicated by the almost uniform absence of tubercle bacilli 

 at the point of inoculation in tuberculous animals and the presence of the bacilli in 

 control animals. 



