VETERIIsrARY SCIENCE AND PRACTICE. 1133 



virulence of rabies virus. The disintegration for a period of five minutes was not 

 sulticient to destroy the virulence. Further tests were made during which it was 

 shown that this destruction of the virulence of the rabies virus was not due to the 

 ffirmation of any inorganic substance in disintegrated brain material. The experi- 

 ments therefore seem to confirm the view that the virus of rallies is <>f an organized 

 nature. 



The passage of rabies virus through filters, 1'. Kemlinger {Aitn. Insl. Pasteur, 

 16' {1904), yo. 3, j)p. 150-164)- — A detailed account is jiresented of e.Kperiments car- 

 ried cut by the author in passing rabies virus through filters of various types. The 

 virus was then studied for the purpose of determining the influence of filtration upon 

 its virulence. The evidence obtained by the author in these experiments indicates 

 that rabies should be classified in a special group of diseases quite distinct from those 

 grouped under jiathogenic protozoa. 



The relation bet"ween modifications of the virulence of rabies virus and 

 alterations in Negri's corpuscles, E. Bertarelli {Centhl. Bakt. u. Far., 1. Aht., 

 Orig., 36 {1904), ^o. 1, ]>p. 4~-ol). — An attempt was made to determine the relation 

 of Negri's corpuscles to changes in virulence in rallies virus, and to alterations in the 

 central nervous system in infected animals. For this purpose dogs and rabbits were 

 used as experimental animals. The results are set down in detail in a tabular form. 

 It was found that Negri's corpuscles were not much affected by extreme changes in 

 virulence. The corpuscles appeared to possess a greater resisting power to various 

 reagents than the surrounding tissues. The author is in doubt, however, whether 

 these corpuscles should be considered as protozoan organisms or as pathological 

 structures containing such organisms. 



Tavo cases of recovery from, experimental rabies, P. REMLiN(iEK and M. 

 Effexdi {Ann. Inst. Pasteur, 18 {1904), No. 4, pp- '241-244).~K detailed account is 

 given of the course and symptoms of two cases of rabies produced by inoculation of 

 dogs. The symptoms in both cases were of a serious nature, and inoculation experi- 

 ments made subsequently showed that both of the dogs were affected w^ith a virulent 

 form of rabies. The complete recovery which took jilace in both cases is considered 

 of sufficient rarity to warrant a detailed account. 



Experimental rabies in birds, J. von Lote {Centbl. Bakt. u. Par., 1. Alt., Orig., 

 33 {1904), No. 6, pp. 741-744)- — Experiments were carried out for the purpose of 

 determining the possibilities of infecting birds with rabies. During these experi- 

 ments it was found that various birds, including owls and eagles, were susceptiVjle to 

 rabies. Chickens and pigeons are less susceptible to the disease. Only a small per- 

 centage of inoculated l)ird.s developed the disease, and many of these cases showed a 

 spontaneous recovery. 



Fowl cholera and fowl plague, M. Hertel {Arb. K. Gesundheilsamte, 20 {1904), 

 No. 3, pp. 4o3-oll, pi. i).— The results obtained by other investigators in the study 

 ot these diseases are briefly pointed out. In the author's expermients the cultures 

 used in the study of fowl cholera were largely obtained from infected geese. Pigeons 

 were lound to be the most susceptible ot all domestic fowls. 



In a series of more than 25 exoeriments, the organism of fowl cholera was obtained 

 in 2)ure culture from the blood of inoculated pigeons. .Since sparrows are almost 

 constantly present in poultry yards and susceptible to fowl cholera, it is suggested 

 that these birds may tiave some influence in spreading the disease. Rats are com- 

 paratively letractory to the disease, while rabbits are very susceptible. The author 

 made a carelul study to determine the natural method of infection in fowls. It was 

 lound possible to infect fowls readily by feeding the virus along with their food or 

 by bringing the virus in contact with the mucous membranes or feather follicles. 

 The possibility of transmission of the disease through the agency of mites and lice 

 must also be admitted. 



