86 EXPERIMENT STATION RECORD. 



were tried during which it was shown that the blood and stomach contents of dis- 

 eased animals were not pathogenic for healthy cattle. 



Feeding experiments with Senecio burchellii demonstrated that this plant is capable 

 of producing pronounced diarrhea together with the characteristic cirrhosis of the 

 liver. The disease in question, therefore, closely resembles the disease produced in 

 New Zealand and Canada by eating S. jacobosa. 



The use of serum in the practical treatment of anthrax, A. Carini {Schweiz. 

 Arch. Tierheilk, 46 (1904), No. 6, pp. 296-304).— Detailed notes are given on 9 cases 

 in which antianthrax serum was used. 



As a result of the author's experience it is concluded that serum therapy may be 

 successfully used in veterinary practice and should be the first choice as a treatment 

 in incipient cases. It may be used in large and repeated doses (150-200 cc. in all). 

 Ten cubic centimeters of the serum is not sufficient to produce a certain immunity in 

 cattle against anthrax. It is better to employ at least as much as 20 cc. 



The immunization of sheep for the purpose of obtaining- a polyvalent 

 serum against anthrax and blackleg, V. Galtier {Jour. Med. Vet. et Zootech., 55 

 {1904), Dec, pp. 705-710).— In the author's experiments, 2 sheep were hyperim- 

 munized by means of repeated inoculations of anthrax and blackleg cultures. 



The first inoculations were with anthrax cultures attenuated by means of LugoPs 

 solution. Later, more virulent cultures were given in increasing doses, followed by 

 blackleg cultures and lastly with mixtures of anthrax and blackleg cultures. In all 

 26 inoculations were given. It was found that the sheep after having received these 

 inoculations at intervals of from 2 to 3 weeks were still in good health. 



The serum obtained from these animals was found to be polyvalent. When 

 injected into rabbits and guinea pigs it protected them against an anthrax inocula- 

 tion 24 hours later and against blackleg inoculation made after a lapse of a similar 

 period. 



Disinfection of animals in preventing foot-and-mouth disease, Blume 

 {Berlin. Tierdrztl. Wchnschr., 1904, No. 52, pp. 874, 875). — The author has found that 

 the hair and skin of living animals may be thoroughly disinfected by the application 

 of a solution of lysofonn soap. This material has no injurious effect upon the animal 

 and is, therefore, to be preferred to corrosive sublimate and similar drugs. The hoofs 

 of animals which have been exposed to infection required more thorough treatment 

 than the general integument. 



A process of disinfection in the prevention of foot-and-mouth disease should be 

 applied to animals which are affected with the disease, animals which have been 

 directly exposed in stalls or pastures, animals which come from localities in which 

 the disease prevails, and animals which have recently been transported in cars or 

 ships wmere infection may have existed. 



The treatment of milk fever with air and iodid of potash, F. thor Stratex 

 (Maanedskr. Dyrlseger, 16 {1904), No. 6, pp. 165-167). — During the past 2h years the 

 author has treated 96 cases of milk fever, of which 72 received iodid of potash, while 

 24 were treated with air. Of the cases treated with iodid of potash, 6 died, while 

 among the 24 treated with air only 1 case resulted fatally and that was due to 

 improper care. 



Necrotic stomatitis, with special reference to its occurrence in calves (calf 

 diphtheria) and pigs (sore mouth), J. R. Mohler and G. B. Morse {U. S. Dept. 

 Ayr., Bur. Anim. Indus. Hid. 67, />/>. 48, pis. .5).— In this country the disease affects 

 calves and young pigs. In calves it has been known as calf diphtheria, but this is a 

 misnomer. 



The literature of the subject is discussed in connection with a bibliography, and 

 notes on the distribution, etiology, and pathological anatomy of the disease. Necrotic 

 stomatitis is due to Bacillus necrophorus and is an acute contagious inflammation of 

 the mouth characterized by ulcers and necrotic patches. The disease occurs most 



