188 EXPERIMENT STATION RECORD. 



the tuberculin test and the further spread of the disease thus prevented. The 

 importance of the lesson taught by these examples is pointed out. 



Immunization against tuberculosis, P. Baumgarten (Berlin. Klin. Wchnschr., 

 .' f . J ( 1905), No. 3, pp. 55, 56). — The author carried on a number of experiments in 

 testing serum immunization of calves against tuberculosis. Good results along this 

 line had already been obtained in experiments with guinea pigs and rabbits. 



The serum used in the experiments came from an animal which had previously 

 received inoculations of human tubercle bacilli and subsequently virulent bacilli from a 

 case of pearl disease in cattle. The animal used for the production of serum had been 

 repeatedly tested with tuberculin without reaction. For the immunization experi- 

 ment 3 calves were used about 3 months old. One of these received 82 cc. of bovine 

 immune serum within a period of 16 days. At the end of that period the calf was 

 inoculated with 5 cc. of virulent bovine tub % ercle bacilli. One of the 3 calves served 

 as a control animal, while the third calf was inoculated with virulent bovine bacilli 

 and also received serum as a curative treatment. 



The control calf became affected with generalized tuberculosis and showed great 

 emaciation. After slaughter abundant evidence was obtained of general infection. 

 The calf which was treated in a prophylactic manner with immune serum w T hen 

 slaughtered at the same time showed no swelling of the lymphatic glands or other 

 alteration which could be attributed to tuberculosis. In the prescapular-lymphatic 

 gland a few yellowish tubercles were found of doubtful nature. The calf which 

 received immune serum for curative purposes was by no means so seriously affected 

 as the control animal and the results obtained with it indicate that an immune serum 

 may be of considerable value for curative purposes. 



Experiments in protective vaccination of cattle against tuberculosis 

 according to the method of von Behring, F. Hutyra (Beitr. Kept. Ther., 1905, 

 No. 9, pp. 1-17). — The experiments reported in this paper were carried out on young 

 cat-tie which received vaccine according to the method of von Behring. The animals 

 were subsequently subjected to intravenous or subcutaneous injections of virulent 

 bovine tubercle bacilli or such bacilli were added to the food. The results of these 

 experiments are presented in great detail in a tabular form. 



The author's experiments agree with those of von Behring in showing that human 

 tubercle bacilli, when injected intravenously into young cattle were capable of con- 

 ferring upon the cattle a high resistance to virulent cultures of tubercle bacilli. Yon 

 Behring' s method is considered as based upon a solid foundation. It is suggested 

 that further experiments are desirable for the purpose of learning the duration of 

 immunity produced by this method. 



Combating bovine tuberculosis according to the method of von Behring, 

 Ebeling (Berlin. Tierdrztl. Wchnschr., 1905, No. 1, pp. 1-5). — The author's observa- 

 tions along this line were made on 1,100 vaccinated cattle, of which 759 received a 

 second vaccination. The nature and theory of von Behring's method are described, 

 and notes are given on the author's method of procedure in making vaccination. 

 The temperatures of animals are taken morning and evening for 2 days before and for 

 8 days after vaccination. 



Among the 1,126 calves vaccinated by the author, 37 were subsequently slaughtered 

 and carefully examined. Of this number, 36 were absolutely free from tuberculous 

 alterations, while in the one remaining animal slight alterations were observed in the 

 right mediastinal and left bronchial glands. The method of von Behring is recom- 

 mended as practical and efficient. 



Anthrax in cattle, horses, and men, D. E. Salmon and T. Smith ( U. S. DepL 

 Agr., Ihir. Anirn, Indus, ('ire. 71, pp. 10). — This is a revision by D. E. Salmon and 

 J. R. Mohler of articles in Special Report on the Diseases of Cattle (E. S. R., 16, p. 

 708) and in Special Report en the Diseases of the Horse (E. S. R., 15, p. 620). 



