192 EXPERIMENT STATION RECORD. 



coitus. The cutaneous plaques or nettle-rash eruptions which appear during the 

 course of this disease are described in detail. The trypanosomes are always found 

 in connection with the plaques. 



The biology of trypanosomes of nag-ana and mal de caderas, W. L. Jakim- 

 off (Centbl. Bakt. [etc.], 1. AM., Orig., 37 (1904), No. 5, pp. 668-678).— The author 

 discusses in a detailed manner the morphology and biology of Trypanosoma brucei 

 and T. elmassiani. 



It was found in inoculation experiments that the trypanosomes of nagana and 

 mal de caderas cause an acute infection in mice and rats which lasts not longer than 

 1 week. In dogs, foxes, guinea pigs, rabbits, and cats the disease shows a slower 

 course, while in goats it assumes a chronic form. Outside of living animals trypano- 

 somes remain alive and maintain their virulence longest in deribrinated blood at a 

 living temperature. Trypanosomes were found to be exceedingly susceptible to heat 

 and disinfection. 



Nagana infection in guinea pigs, Markl (Centbl. Bald, [etc.], 1. Abt. } Orig.. 

 37 (1904), No. 4, pp. 530-537). — Trypanosoma brucei was used in these experiments 

 and was found to produce death after the inoculation of guinea pigs within from 11 

 to 80 days. Detailed notes are given on a number of cases. The incubation period 

 varied from 3 to 8 days. In almost all cases the progress of the disease appeared to 

 be without striking symptoms, but ultimately death occurred very suddenly. 



Trypanosomiasis and tsetse-fly disease in French Guiana, A. La vera x 

 (Compt. Rend. Acad. Sci. [Paris'], 140 (1905), No. 2, pp. 75-78). — Brief notes are given 

 on the distribution of tsetse flies and other biting insects in French Guiana and on 

 the relation between these insects and trypanosomiases. 



Equine piroplasmosis or "biliary fever," T. Bowhill (Jour. Hyg. [Cam- 

 bridge], 5 (1905), No. 1, pp. 7-17, pis. 3). — This disease is of great importance in certain 

 parts of Cape Colony for the reason that recently imported horses may develop an 

 acute and fatal form of the disease. The distribution of the disease is briefly dis- 

 cussed and notes are given on the pathogenic blood parasite which occurs in various 

 forms. Apparently, the range horses of South Africa are somewhat immune to the 

 disease, and the author believes that animals which have recovered from one attack 

 are immune. A number of secondary affections may follow upon the occurrence of 

 the disease. 



The diagnosis of rabies, L. Luzzani (Ztschr. Hyg. n. Infectionskrank. , 49 (1905), 

 No. 2, pp. 305-324). — During the author's observations and experiments with this 

 disease results were obtained which indicate that Negri's corpuscles may be connected 

 with the etiology of the disease. 



The author's observations were made on 179 cases, of which 165 were in dogs, 12 

 in cats, 1 in a beef animal, and 1 in a horse. Among this number 107 were exam- 

 ined for the presence of the parasite and it was found in 102 cases. The author 

 believes, therefore, that in suspicious cases a positive diagnosis may be reached if the 

 endocellular form of the protozoan is found in the nervous system. 



The action of centrifugation of rabies virus, P. Remlixger (Compt. Rend. 

 Soc. Biol [Paris'], 58 (1905), No. 1, pp. 27, 28).— In experiments carried out by the 

 author it was found that emulsions of rabies virus, diluted at the rate of from 1 to 

 50 and 1 to 100 and maintained in the centrifuge revolving at the rate of 100 times 

 per minute, showed a loss of virulence in the supernatant portion after a period of 1 

 hour. The virulence in this portion of the material was diminished gradually. The 

 author believes that these experiments show that rabies is due to a micro-organism, 

 but that this organism is probably ultra-microscopic in size. 



Fowl plague, E. Leclainche (Rer. Gin. Med. Vet., 3 (1904), No. 26, pp. 49-54).— 

 This disease, which is also called bird pest, belongs with the group of hemorrhagic 

 septicemia. Notes are given on the symptoms, diagnosis, pathological lesions, and 





