v ]■ i i- 1:1 v\m \i i-.dk in i-:. 595 



diagnosis, treatment, and prevention of glanders, with notes on the use of mallein 

 and on oflBcirl inspection for glanderous horses. 



The Arkansas law relating to this matter pro> ides for notification of horses affected 

 with the disease, isolation of such animals, the prevention of traffic in affected hoi 

 or mules, the use of mallein test, and thorough disinfection of the premises after an 

 outbreak of glanders. Brief notes are also given on the present prevalence »»f glanders 

 in Arkansas. Details of inspection work carried oul under this law in h (04 are fur- 

 nished by .1. I-'. Stanford. 



A case of uveitis malleotica, J. i>k II van i Forlschr. Vet. Hyg., ■■' 1905 ), No. 3, 

 pp. '/'.>, 50). — The literature relating to the occurrence of glanders in the eyes of h 



is briefly discussed in connection with a descripti* f the Bymptoms as observed by 



the author. An examination of a case which came under observation disclosed the 

 t'a.t that the glanders bacilli were presenl in pure cultures in the exudate from the 

 \\\- and choroid coat. 



The action of certain oxidizing- substances upon the toxin of tetanus, 

 ( '. Paderi [Arch. Farmacol. Sper. e Sci. Aff., /' (1905), No. t,pp. 8-28). — The author 

 studied the effect upon tetanus toxin of certain oxidizing substances including ozone, 

 permanganate of potash, and sulphate of soda. 



It was found thai ozone, on accounl of its oxidizing property, greatly irritated the 

 tissues with which it came in contacl and .was, therefore, somewhat injurious to the 

 organism. It also destroyed the tetanus toxin wherever it came in contact with it. 

 Ozone, however, apparently had no effect upon the tetanus toxin circulating in the 

 blood, since it could not bebrought in contact with it. Similarly, permanganate of 

 potash, when brought in contact with tetanus toxin outside of the organism, quickly 

 destroyed it. but had no effect upon the toxin circulating in the living animal organ- 

 ism. Sulphate of soda was even less effective. 



It appears that the three oxidizing substances studied by the author are not capa- 

 ble of increasing the oxidizing power of the animal organism toward toxic substances 

 in circulation in the tissue-. 



Studies and observations on rabies, E. Barterelli (Centbl. Bakt. [etc.'], 1. 

 AbL, Orig., 39 I 1905 i, No. 7. pp. 899-409). — It was found during the author's study 

 that the salivary glands of rabbits affected with rabies may sometimes become infec- 

 tion-, particularly if an unusually virulent virus is used. 



The author studied also the relation between the appearance of Negri's corpuscles 



and the use of fixed virus. Experiments in the transmission of rallies to cold-bl led 



animals showed that the virus has no effect upon them, being excreted rapidly after 

 injection. A study of the saliva of a man affected with rallies showed thai this mate- 

 rial was exceedingly virulent. 



ftabies in Muridae, ( '. Franca I Compt. Rend. Soc. Biol. [Paris], 58 I 1905), No. 9, 

 pp. $10, 411). — It was found possible to produce rabies in various species of Mu< and 

 Arvicola by inoculation. 



The form of the disease was usually paralytic, the symptoms being quite pro- 

 nounced in all cases. A histological examination disclosed the presence of diffuse 

 infiltration of leucocytes in the medulla oblongata and nerve ganglia, bul none of the 

 nodules described by Nan < rehuchten. By means of the silver met hod recommended 

 by Ramon-y-( !ajal lesion- are demonstrable in the nerve fibrillar 



Treatment of rabies with radium, G. Tizzoni and A. Bongio^ v\m I Centbl. Bakt. 

 [etc.], i. AbL, Orig., 89 [1905), No. ',. pp. A number of laboratory animals 



were inoculated with fixed virus and subsequently treated with radium rays. At the 

 time of the report it was 2 month- since inoculation and the animals were considered 

 as cured. 



The curative action of radium was tested quite extensively. It was found that 

 L0,000 radio-active units applied directly upon the eye of inoculated rabbits had 

 the same effect whether the application was continued for s hour- or whetfcu 



