VETERINARY MEDICINE. 811 



to be possible to protect dogs against rabies by a single injection for a period of at 

 least one year. 



The so-called premonitory fever as a symptom of experimental rabies, J. 

 von \JyiE{Centbl. Bakt. [etc.], i. Abt., 0rig.,39\ 1905), No. 1, pp. 82-85).— From care- 

 ful determinations of the temperature of normal rabbits the author believes that the 

 body temperature is sufficiently regular to prevenl anj confusion between normal 

 temperatures and t lie fever which is regarded as premonitory of an outbreak of rabies. 

 This fever was considered as a perfectly natural occurrence indicating the beginning 



Of the disease. 



The action of radium rays upon the virus of rabies in vitro and in the ani- 

 mal organism, <i. TizzoNi and A. Bongiovanni {Centbl. Bakt. [etc.], l. AbL, Orig., 

 39(1905), No. ?, pp. 187-189) . — In the authors' experiments il was found thai the 

 virus «.i' rabies in vitro or in the animal organism is rapidly destroyed under the 

 influence of radium rays. 



Sleepy disease of chickens, C. Da.mmaxx and 0. Manegold [Beat. Tierarztl. 

 Wchnschr., IS 1 1905), No. 50, pp. 577-579, fig: 1).— On an estate in Westphalia a dis- 

 ease broke ou1 among chickens and affected nearly all of a flock of one hundred. 

 The affected fowls showed a roughness of plumage, swollen eyes, paleness of the 



;omb, and lameness. The appetite appeared to be fairly g 1 during the course of 



the disease. 

 When a post-mortem examination was made, striking symptom., of hemorrhagic 



septiramia were found. The musculature was permeated with bloody effusions and 



red spots were observed in the mucous membrane of the intestines. The spleen was 

 considerably enlarged, and hemorrhagic patches were observed in other parts of the 



body. A. capsule-bearing streptococcus was found in large quantities in the hi 1. 



This organism is described under the name Streptococcus capsulatus ■gallinarum. It 

 is either aerobic or anaerobic, and differs in many respects according to the animal 

 in which it is inoculated or the artificial medium in which it is cultivated. It is 

 quite susceptible to heat and is destroyed in 2 minutes by exposure to a 1 per rent 

 solution of carbolic acid. 



The disease may he readily transmitted by inoculation of virulent blood to other 

 chickens. When thus inoculated the most striking symptom in the fowls is sleepi- 

 ness, and this symptom determined the name of the disease. The disease may be 

 transmitted by subcutaneous inoculation to pigeons, rabbits, and white and gray 

 mice. 



The protective properties of blood from animals affected with fowl cholera 

 and immune to aggressin, E. Weil (Arch. Hug., 54 (1905), No. % pp. 149- 

 184 •■ — A thoroughly protected immune serum appears not to exist in a ease of fowl 

 cholera. The positive results obtained by active immunization, however, make it 

 probable that blood of animals treated with an exudate containing aggressin con- 

 tains protective substances. 



The author's experiments were carried OUl 0D rabbits and the immune serum used 

 in the experiments came from rabbits which have been immunized by means of a 

 very virulent culture <>f fowl cholera bacillus. Serum thus obtained was tested on 

 mice, and it was found that 0. l cc. of the serum was sufficient to protect mice against 

 a bacterial dose which killed control animals in less than L'4 hours. When tested on 

 rabbits it was found that from \ to 1 cc. of the protective serum was a Bafe and effect- 

 ive dose for one of these animals. Experiments with pigeons and chickens were not 

 satisfactory. When the protective serum and the active virus were inoculated at 

 the same time it was found t hat the serum was sufficient to prevent the development 

 of the disease in mice, rabbits, and guinea pigs. 

 23786— No. 8— 06 7 



