916 EXPERIMENT STATION RECORD. 



in question is apparently closely related to malaria. The development of fever 

 o.curs suddenly and assumes an acute form. Death may result within 2 or 3 

 days. 



Quite satisfactory results were obtained from the use of subcutaneous and 

 intravenous injections of quinin. The blood parasites may be easily obtained 

 and stained for examination. A detailed description is given of these parasites 

 in their different developmental forms. Intravenous inoculation of blood from 

 affected animals failed to produce the disease in horses, rabbits, and guinea 

 pigs. Apparently the disease is transmitted by means of insects, perhaps 

 mosquitoes. 



The bacterial flora of the nasal cavity of the horse, De Angelis (Rec. 

 Mr<l. Vet., 83 ( 1906), No. I. pp. 31-35). — According to the author's investigations 

 ;i staphylococcus and streptococcus are constantly found in the nasal cavity of 

 I lie horse. These organisms are not pathogenic for laboratory animals, but may 

 produce local or even generalized infection in the horse. These micro-organisms 

 are identical with nonpathogenic forms in their morphological and pathological 

 characters. Repeated occurrence of them in horses does not produce immunity. 



The occurrence of the tetanus bacillus in animal feces, A. Hoffmann (Hyg. 

 Rundschau, 15 {1905), No. 2',. ]>j>. 1233-1239). — In the author's experiments 

 cultures were used from the feces of sheep, horses, and cattle in inoculating 

 mice for the purpose of determining whether tetanus bacilli were contained in 

 this material. In the 22 experiments carried out along this line, tetanus was 

 produced in only one case. It appears, therefore, that the feces of animals 

 which bear wounds at the time may contain tetanus bacilli in sufficient numbers 

 to cause infection. 



The destruction of rabies virus in the peritoneal cavity, P. Remlingeb 

 (Compt. Rend. Soc. Biol. [Paris], 59 (1905). Ao. 38, pp. 689, 690).— It has long 

 been known that the virulence of pathogenic bacteria may be increased when 

 these micro-organisms are kept in collodion sacs, or otherwise in the body 

 cavity of susceptible animals, and also by repeated passage by means of hypo- 

 dermic or intravenous inoculations through animals. When rabies virus, how- 

 ever, is placed in the body cavity of dogs and rabbits the opposite effect is 

 ol isorved. 



In the author's experiments samples of virus thus treated were removed 

 every day and used for inoculating experimental animals. It was found that 

 none of the animals inoculated after more than 24 hours had passed was 

 affected. The rabies virus was completely destroyed by remaining in the peri- 

 toneum for 24 hours. ^ 



The diagnostic value of Negri's corpuscles, Bohne (Ztschr. Tlyg. u. Infcc- 

 Honskrank., 32 (1905), No. 1. pp. 87-96, pi. 1).—In the investigations reported 

 in this paper the author came to the conclusion that Negri's corpuscles must be 

 looked upon as of specific diagnostic value for rabies. If tissue from suspected 

 animals is embedded by the quickest known methods it is possible to arrive at 

 a. positive diagnosis within a few hours. In case the result is negative it is 

 desirable to make a test by means of animal inoculation. The exact nature of 

 Negri's corpuscles is not certain, and in the present state of knowledge the 

 author believes that their parasitic nature is somewhat doubtful. 



The nonvirulence of milk of rabid herbivorous animals subjected to intra- 

 venous injections of rabies virus, J. Nicolas (Jour. Med. Vet. et Zootech., 

 56 (1905), Dec. pp. 121-726).— The author's experiments were carried out on 

 goats and cows, and the milk obtained from inoculated animals was used in the 

 inoculation of laboratory animals. 



It was found that the milk and mammary tissue of herbivorous animals 

 suffering from rabies is never virulent. In goats and cows subjected to 



