330 



Two horses on the place, one in good condition and apparently 

 healthy, the other in very poor condition being practically skin 

 and bones and very weak. This animal presented the following 

 symptoms: An oily sticky, bilatoral, nasal discharge; both sub- 

 maxillary glands swollen and firmly adherent to the jaw-bones 

 and an occasional cough. The animal walked with a stiffened 

 gait, with head hanging low, but seemed to have a ravenous 

 appetite. 



Each horse received an intradermal injection of four drops of 

 Malleins at 1 1 :00 a. m. An examination at 4 :00 p. m. showed 

 swellings 2 inches in diameter at the point of inoculation in each 

 case. On the horse showing clinical symptoms no sensitiveness 

 was apparent, but the swelling on the other horse was quite 

 painful. 



A further examination was made the following day and there 

 was no apparent reaction to the intradermal test in the clinical 

 case the swelling being the same size and without heat or tender- 

 ness. In the other horse, however, a swelling appeared which 

 was 4 inches in diameter and extremely painful. From its lower 

 edge, two corded lymphatics extended for an inch toward the 

 point of the shoulder. 



At 11 :00 a. m. each horse was given one drop of opthalmic 

 malleins in the left eye and the clinical case ordered to the quar- 

 antine station where it was taken on a dray. It was in a mori- 

 bund condition when it reached the station and fell from the 

 dray as the corral was reached. At this time there was con- 

 siderable muco-purulcnt discharge from the left eye — four and 

 one-half hours after instillation of opthalmic malleins. 



The horse was killed where it lay and a post-mortem exami- 

 nation reaveled the following: 



The nasal septum, turbinated bones and superior maxillary 

 sinuses were covered with ulcers and purulent discharge. In 

 places the nasal septum was nearly eaten through. The lungs 

 showed four adhesions to the costal plura and all the lobes were 

 filled with shot-like nodules. All the other organs of the body 

 were apparently normal. 



An examination of the remaining horse on the following day, 

 24 hours after instillation of o])(halmic malleins. revealed a very 

 pronounced reaction. The reaction to the intradermal test was 

 considerably intensified, the swelling now being 6 inches in 

 diameter, very y)ainful and with three corded lymphatics extend- 

 ing to the point of the shoulder. The animal presented a very 

 depressed appearance, standing in one place practically all the 

 time with head hanging and caring little for food of any kind. 

 The horse was removed to the ffuarantine station and directions 

 were given for a com])letc and thorough disinfection of the 

 premises. 



A few days later this animal was killed and on post-mortem 

 examination both lungs were found to contain shot-like glanders 



