FURTHER 8TUDIKS ON UREIXE. 537 



tu empliasize tliat tbe relation of ureiue to diabètes deserves special and 

 detailcd study. 



Tiiire are two questions whicli will arise justly aud inevitably: 1) Is 

 nur orgauic liquid, urcine, a cbemical unity? 2) Is ureine a newly disco- 

 vered cbemical body? 



Botb questions I fcel justified to answer in the affirmative. 



1) An organic liquid wbich always possesses the same cbemical, phy- 

 sical and pbysiological propcrties is in all probability a cbemical unity. 



2) Ureine bas I)ecn uidiiiowii heretofore, for it differs from any otber 

 substance dcscribed by otber autbors. It certainhj has nofJiing in common 

 witli Fouchd's matière extractive^). Poucbet evaporated 30 Liter (!) of 

 urine and obtained a «(res minime proportion de ces composés alcaloidiques» 

 (probably only a few drops), wbile wo can obtain from 30 Liter of urine 

 about COO gramni of ureine. Tbis matière estractive bas beeu prepared in 

 an entirely différent way from tbc metbod of preparing ureine. 



Poucbet exposed tlie urinary residue to a proloiiged température of 

 70 — 80° C. By exposing ureine to a température of only 75° C. we notice 

 the visible formation of vapors containing nitrogen and carbon, — in otber 

 words, ureine is slowly dccomposed by a température of 70 — 80° С. Pou- 

 cbet precipitated bis alcaloïdes tvith tannic acid («préparer Tannâtes d'al- 

 caloïdes qui sont décomposés par l'bydrate de plomb»), îvliile iireine is not 

 precipitated hy tannic acid. Poucbet says furtbermore: «Cette substance 

 resinifie par Acide Cblorbydrique». Ureine is not resiuified by muriatic 

 acid. Tbis «matière» bas a dark brown color, wbile tbe color of ureine is 

 goldenyellow. 



PoucheVs «matière extractiven is evidently an alcaloidal bodi/, which 

 occnrs in such minute quantities in the human urine, as to offer no further 

 interest. 



Wbitb tbe firm bope, tbat my observations will receive the kind 

 attention of tbe Pliysico-Matbematical Class of the Imperial Academy of 

 Sciences, I berewitb respectfully submit my second paper to tbe said class 

 of tbe Imperial Academy. 



1) Comptes rendus de TAcad. de Sciences de Paris, 18S3, p. 1560. 



Фпз.-Ыат. стр. 139. 9 36* 



