INTRODUCTION. 
the foremost pharmacologist of the world. With Daniel Hanbury, he 
had just completed the monumental work on European and Oriental 
drugs, (including the principal drugs of other parts of the world) 
known as the Pharmacographia, and was ambitious to continue, in like 
manner, with the medicinal products of North America. In July, 1894, 
Professor Fliickiger visited America, where he was the guest of the 
renowned American pharmacists, Dr. Edward R. Squibb, of Brooklyn, 
and Dr. Frederick Hoffman, of New York City. He had arranged to 
visit Cincinnati and consummate here a plan for the detailed study of 
the North American pharmacography, but a period of intense heat 
then chanced to prevail throughout America, and the aged professor 
was forced, reluctantly, to abandon his journey to this city. The writer 
then selected and forwarded to Professor Flickiger, for review, several 
cases of books dealing with the early American materia medica, such as 
domestic writings, early American travels, Eclectic and Thomsonian 
literature, as well as publications of primitive days concerning family 
medicines and connected preparations. These very much delighted 
and even surprised Professor Fliickiger, both as regards variety and 
contents. It was then tentatively arranged that a Pharmacography 
of North American Medicinal Plants and Drugs should be at once in- 
augurated, the responsibility of the chemistry and the correlation of the 
chemical and proximate products derived from the American materia 
medica being assumed by Professor Fliickiger, as well as the system- 
atic research of foreign publications in those directions. He designed, 
also, to institute a series of original investigations in his laboratory, 
at Strassburg University. The Lloyd Library seemed, even then, com- 
petent to furnish the historical data sufficient to establish the records 
of the plants considered, this writer (John Uri Lloyd) accepting the 
responsibility of the history, including the sophistications and descrip- 
tions of the parts used in medicine, whilst the botanical history, re- 
lationships, and kindred descriptions were to be the care of Mr. Curtis 
Gates Lloyd. The publication was thus to partake of the plan of both 
Drugs and Medicines of North America, and the Pharmacographia of 
Fliickiger and Hanbury, so well known and so thoroughly established. 
The work was accordingly commenced, and several historical articles 
were prepared by the writer, a few of which were forwarded to Pro- 
fessor Fliickiger. The unfortunate and lamentable death of that world- 
renowned pharmacologist, within a very short time after his return 
to Europe, terminated the enterprise, bringing to the writer one of the 
greatest disappointments of his life. 
Of the drug articles thus prepared for Professor Fliickiger, two 
were subsequently published in the American Journal of Pharmacy, 
one, titled The California Manna,* appearing in July, 1897, and the 
* When Prof. Fliickiger visited America (July, 1894), he hoped to obtain 
historical data that would enable him to give the records of several interest- 
ing American productions. In this he failed, and he then associated in his 
behalf the services of the author of this paper. After much of the work had 
been done, the death of Prof. Flickiger interrupted the investigation. | 
These papers (some of them) passed into possession of Prof. Ed. 
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