54 :  CINCHONA BARKS. 
The extracts of other Cinchona barks afforded by the same treat- 
ment no caffeeic acid. This investigation was instituted in conse- 
quence of crystals of caffeeate of quinine having been found in the 
mother liquids obtained from Cinchona cuprea in the quinine manu- 
factory at Milan. . 
All the Cinchona cuprea which I have obtained from London and 
New York, as also from Jobst’s manufactory, near Stuttgart, and, 
furthermore, e. g., that which J have inspected in large amounts in 
Zimmer's manufactory at Frankfort, always represented one and 
the same product. Triana states that the districts southeast of 
Bogota, mentioned on page 20, also furnish the same bark; the 
latter he derives with precision from the there described Remzazia pe- 
dunculata, to which thus the bark from Bucaramanga may prob- 
ably also belong.’ 
Among the: Cinchona cuprea which reached France, small 
amounts of a bark have, however, been found by Von Arnaud,’ 
which, according to Planchon, is essentially distinct from my Cin- 
chona cuprea. As Arnaud has discovered in that a new alkaloid, 
cinchonamine, the respective variety may here be designated as 
Cinchonamine bark. It is, as stated by Planchon,* mostly deprived of 
the warty cork, and displays upon a transverse section about 10 rows 
of small, isodiametrical or polygonal cells, which, toward the interior, 
gradually become extended in a tangential direction, and thereby 
impart to the transverse section a peculiar delineation. In the 
bast there are very numerous, densely crowded fibres with consider- 
able cavities, in radial rows, which are separated by medullary rays 
of from 4 to 5 cells in width. On a longitudinal section the fibres 
appear slightly elongated, and short sclerenchyma cells and lacti- 
ciferous ducts are wanting, while my Cinchona cuprea is particularly 
characterized by the abundant development of groups of scleren- 
chyma.’ The bast of Cinchona cuprea displays, as may be observed 
in Plate VIII, two distinct strata; according to Planchon’s intima- 
tion this is not the case in the bast of the Cinchonamine bark, 
although, indeed, here also the fibres in the outermost bast layers 
occur somewhat more numerously than in the inner. 
1 Fourn. de Pharm., V (1882), p. 567; also Pharm. Journ. XII (1882), p. 861. 
2 Repertoire de Pharm. 1881, p. 507. 
8 The name cévchonamine was already bestowed by A. C. Oudemans, in 1879, to 
another alkaloid, which has not been met with again since it was discovered. 
* Journ. de Pharm. V (1882), p. 354, ‘‘ Quinquina A cinchonamine;” and VI, p. 89, 
“Note sur les Ecorces de Remijia. 
® | unfortunately did not succeed in obtaining the Cinchonamine bark. It is presum- . 
ably the same bark which, according to the Pharm. Yourn. XI, p. 895, als od 
once in 1881, in London. . F ~— 895, also appear 
