SUBJECT INDEX 



413 



Mitoclioiulria, mutants in Sctirosporu, 240, 



254-257 



mutants in yeast, 241, 254-257 



pancreas, guinea pig, plate \1V 



replications, 235 



RNA in, 247-248 

 Mitosis, 71-73 



bacteria, 114, 142, 183 



crossing over, 359-370 



DNA content, 185 

 Mitotic crossing over, see Somatic crossing 



over 

 Monosomic, 106 

 Mosaic, 374-375 

 Mouse, nucleotides per maj) unit, 172 



f-locus, 168 

 Multiple allele. 171 

 Mutable genes, 56-57, 341-346 

 Mutable unit, see Unit of mutation 

 Mutagens, acridine dyes, 232, 255-256 



adenine, 212-213 



alkylating agents, 217 



2-amino purine, 169, 212 



5-bromouracil, 169, 213-214 



caffein, 212 



epoxides, 217 



free radicals, 223, 229 



heat, 216 



nitrogen mustards, 217 



nitrous acid, 36-38, 169 



nonchromosomal factors, 232, 251-256 



peroxide, 223, 229 



proflavin, 216 



sulphur mustards, 217 



UV, 210, 227-229 



X-ray, 103-104, 217-218, 219-225 

 Mutant, auxotrophic, 274 



constitutive, 334-338 



cryptic, 332-333 



definition, 35 



increase in proportion, 208-209, 375 



lethal, 221-222, 302 



temperature sensitive, 277, 297, 301- 

 302 

 Mutation, and gene replication, 209-210 



auxotrophy, 274 



chemically induced, 169, 212-217, 231- 

 232 



chemostat, 207-209 



definition, 35, 40-43 



directed, 231-232 



Mutation, cn/xrne svnthcsis, 334-338 



forward and back, 39-40, 43, 169-170 



independence, 49-50 



induced by nitrous acid, 36-38, 215-216 



kappa, 264 



lethal, 221-222, 302 



nonchromosomal factors, 232. 251-257, 

 377-378 



point mutations, 43, 217-219 



position effect, 339-346 



radiation induced, 219-231 



randomness, 43-53 



rates, 53-57, 208-209, 375-376 



somatic cells, 372-378 



temperature and, 210, 229-230 



timing, 56-57, 342-346 



unit, 40-43, 150-152 

 Muton, 166-168, 170 

 Mvcelium. 70, 260 

 Myoglobin, 289 



N's, 188-192 



Neurospora, arginine synthesis, 29-31 



complementation, 291-293 



crossing over, 75-78 



gene action, 273ff 



life cycle, 67 



meiosis, 68-69 



mutation. 218 



nucleotides per map unit, 172 



poky mutant, 238-240, 254-257 



RNA synthesis, 314 



suppression, 297-298 



tryptophane svntheta.se, 276-280 



tyrosinase, 31 

 Nitrogen base, 4 

 Nitrous acid, 36-38, 169 

 Nonchromosomal inheritance, 234ff 



criteria, 241, 243 



directed mutation, 232 



F factor, 144 



hypotheses, 242-244, 268-269 



prophage, 148 

 Nondisjunction, 91-93 



Aspergillus, 369 



E. coli, 135-137 

 Non-Mendelian inheritance, see Nonchro- 

 mosomal inheritance 

 Nuclear envelope, 176, 245, plates IX, XV, 



XVI 

 Nuclear transplantation. 351-352 



