MECHANISMS OF GENE ACTION 



279 



■9.8- 



8.0- 



-1.9 

 ■1.9- 



■9.9^ 

 -9.0- 



-5.6- 

 -5.9- 



-1.0 ^^ 



5.5- 



-3.6 ^1—2.6 



-3.7- 



-3.3 >■ 



-3.8- 



-1.7- 

 -1.9- 



-3.4- 

 -3.9- 



U 



B-4 fi-6 B-2 B-5 B-] B-3 A-1 



A A 



8 17 



■ ■ ■ ■ 



IZI 



-1.3 



f .24 

 .45 H 



■1.3- 



■1.7- 



-1.5- 



-2.6 



-1.5 



-2.4 



3.8 



■1.4- 



-1.5 ■ 

 -1.6 ■ 

 -1.5 



-.26^ 

 33-^ 



-.384 



-.0054 



-.007- 

 -.006- 

 -.013- 



-2.3- 

 -3.5- 



-2.0- 

 -2.4- 

 •3.6- 

 ■3.6 



•4.2 

 -3.1- 



-2.4 



FIGURE 10.3. Genetic map of the tryptophane synthetase region of E. coli. Pre- 

 liminary map of mutational sites for genes A and B. The black bars indicate the location 

 of mutationally altered sites which lead to inability to form the A or B protein. The 

 thin lines represent mutationally altered sites in mutants producing A-CRM or B-CRM. 

 The values given were obtained in transduction experiments (the arrow indicates direc- 

 tion of transfer) and are based on the number of tryptophane-independent colonies 

 which were observed relative to a control transduction from histidine dependence to 

 independence (after Yanofsky, 1960, Bocf. Reviews, 24:221). 



