VETERINARY SCIENCE AND PRACTICE. 191 



dnya after the inoculation of lot 2, the pigs of this lot began to die, 

 and at the end of 45 days onl}^ 56 were left of the 320. 



In order to determine whether the inoculation with Detmers' virus 

 was the cause of the outbreak of the disease, 10 average pigs were 

 selected from lot 2 for special experiment. The temperatures of these 

 pigs were taken and were found to range from 101. 1 to 109° F. Only- 

 one of the pigs had a normal temperature. Each of these 10 pigs 

 received 5 cc. (10 full doses) of a check culture of Bacilhbs suis. In 

 some of them a slight rise in temperature was noticed on the second 

 da}', as a possible effect of the lymph. In others no effect whatever 

 was noticed. The pig which had the normal temperature at the 

 beginning of the experiment was the only one which survived. The 

 authors believe that all those which died were infected with swine 

 plague before the beginning of the experiment. The observation of 

 temperature of pigs seems to be a valuable method of diagnosing swine 

 plague before other symptoms are manifested. 



The regular dose of the virus is from 0. 1 to 1 cc. , but the authors 

 found by experiment that pigs could receive 25 times this amount 

 without permanent bad effects. It was concluded, therefore, that pro- 

 tective inoculation when carefully performed can not cause an outbreak 

 of swine plague. Notes are given on an outbreak of swine plague in 

 a herd of a farmer, from which it is apparent that pigs may be infected 

 Avith swine plague for a period of 33 days before deaths begin to 

 occur. 



Nine hundred and fifty-five pigs belonging to farmers in the State 

 have been inoculated with the Detmers virus and not one of this num- 

 ber has died of swine plague, although many of them have been 

 exposed. The authors believe that the method can be so perfected as 

 to be of considerable practical value but do not recommend its general 

 adoption until further experiments have been conducted. 



Ne-w investigations on Trichophyton minimum, Le CalviS and H. 

 Malherbe {Arch. Parasit., 2 (1899), jVo. J^, pp. J^89-503, Jig.l).— The 

 authors give a detailed description of the dermatomj^cosis produced by 

 this organism. From a study of the circumstances under which out- 

 breaks of the disease were observed it is concluded that the fungus 

 lives during the winter in a vegetative condition in the soil or filth of 

 stables. 



The mycelium of this organism secretes about itself a sort of sub- 

 stance of a mucoid nature. Some experiments were conducted to 

 determine the chemical nature of this substance. Boiling water, dilute 

 mineral acids, dilute bases, and dilute organic acids had no effect at all 

 upon the mucoid matter, except in the case of acetic and hydrochloric 

 acids, which seemed to clarify the substance. Numerous other tests 

 were made, with the result that the substance is believed to be of a 

 1710— No. 2 7 



