21^2 EXPERIMENT STATION KECOKD. 



Observations concerning the significance of streptococci in 

 comparative pathology, V. A. Moore {Amer. Vet. Rev.^ '23 {1900)^ 

 JVox. UK j>p. 6S7-6!J7; 11, 2>p. 771^-787; 12, pp. 8Ii9-860,f(js. H).— 

 The author gives a ])rief review of the literature on streptococcus and 

 an account of the systematic position of this genus. A bacteriological 

 investigation was made of i cases of suppurative cellulitis of cows, in 

 which the foot or leg was affected. Streptococcus was found to be 

 present in all cases. Other cattle inoculated with pure cultures of 

 these organisms developed the same sj-mptoms. Kabbits which were 

 inoculated with pure cultures died with septicjemia within 48 hours 

 after inoculation. 



Samples of milk were taken from y different cows which were suffer- 

 ing from mastitis. The milk samples were taken with strict antiseptic 

 precautions. Streptococci were found in considerable numbers in 6 

 out of the 8 samples. In 2 cases of foot rot of sheep, a form of strep- 

 tococcus was found which proved fatal to rabbits when inoculated 

 hypodermically. A liacteriological investigation demonstrated the 

 presence of streptococcus in the following diseases of the horse: Fistu- 

 lous withers, poll evil, peritonitis, omphalophlebitis, septic pneumonia, 

 strangles, and infectious pneumonia. 



The author also made studies of distemper and rabies of the dog. 

 Streptococcus was found to be present in cases of distemper but not in 

 rabies. Brief notes are presented on the use and importance of anti- 

 streptococcic serum. 



The curability of glanders, J. McFadyean {Jour. Co-mp. Path, and 

 TJur.. 13 {1900, JTo. 1, pp. oo-o9). — The author conducted an experi- 

 ment to determine the therapeutic action of mallein upon glanderous 

 horses. A horse with clinical symptoms of farcy was tested with 

 mallein on November 4, 1898, and reacted in a typical manner with 

 elevation of temperature and swelling at the point of injection. The 

 highest temperature recorded was 105.4^. On November 15 the 

 horse received 6 cc. of mallein and after 15 hours exhibited a tempera- 

 ture of 105.8^. On November 26, 10 cc. of mallein was injected into 

 the horse, with a consequent sharp temperature reaction. A dose of 

 20 cc. of mallein was administered on December with similar results. 

 Further injections were made on December 14, 20, 28, and January- 

 13 with 40, 80, 100, and 120 cc. of mullein, respectively. On Feb- 

 ruary 10 the horse was examined and the farcv lesions were found to 

 be healed. The animal was tested with 1 cc. of mallein on the same 

 date and failed to react. On March 27 a second dose of 1 cc. of 

 mallein was given, with no temperature reaction. On April the 

 horse received 100 cc. of mallein with the result that the temperature 

 rose to 103. 8^^. The same dose repeated on April 24 ]ii-oduced a tem- 

 perature of 103". 



The horse was apparently cured of the original attack of glanders. 



