490 EXPERIMENT STATION RECORD. 



fomi or character while hving for a considerable time in the body of frogs. It was 

 impossible to note any such changes in the bacillus after remaining from 6 to 9 

 months in the organism of the frog. The pathological properties of the tubercle 

 bacillus were not modified by this long sojourn in the frog. Experiments showed 

 that bacilli which had remained 6 months in the peritoneal cavity of the frog caused 

 death from generalized tuberculosis in the guinea pig at the usual time after inocu- 

 lation. 



Generalized tuberculosis in the horse, J. M. Kxipscheer {Tijdschr. ]'reartsenijk 

 en Veeti-i'Jt, ,.'7 (1000), Xo. J, pp. lGJ-167) . — A discussion of clinical symptoms and 

 poM-ini>iltiii lindinirs. 



The susceptibility of the ass to tuberculosis, V. (taltier {Jour. Med. Yet. et 

 Zootech., 5. ser., 4 {1900), pp. 17-8^, ficjif. 2). — It has long been known that the ass 

 possesses a high resisting power to tuberculosis. During experiments which were 

 conducted by the author it was found that of 11 asses which were inoculated in the 

 jugular vein with tubercle bacillus all became infected, and 8 died. The other 3 

 recovered. The author concludes that, although the ass is very resistant to this dis- 

 ease, it may become infected naturally or experimentally. 



The diagnostic and therapeutic significance of tubercle bacilli and other 

 bacteria in sputum, L. Brieger {Berlin. Klin. Wchn.^chr., 37 {1900), No. IS, pp. 

 272—274). — Notes on the frequency of tubercle bacilli in the sputum of tuberculous 

 patients. 



Tuberculins and their use, E. A. de Schwei.vitz {Jour. Ainer. Med. Assoc, 34 

 {1900), Xo. 15, ]jp. 898-900) . — The author describes the difference in the methods of 

 production and the nature of the old and new tuberculins. It is stated that the 

 prospect of using the products of the tubercle bacillus freed from necrotic princii)les 

 for the treatment of incipient tuberculosis is somewhat encouraging. 



Tuberculin, and the early diagnosis of tuberculosis, B. FrXxkel {Berlin. 

 Klin. Wclinschr., 37 {1900), No. 12, pp. 255-258) . — A discussion of the value of tuber- 

 culin in the practice of human medicine. 



Morphological changes in anthrax bacillus during its dissolution by 

 pyocyanase, R. Emmerich and Saida {Centbl. Bakt. u. Par., 1. Ahi., 27 {1900), No. 

 22-23, pp. 776-787, pi. 1). — The authors experimented with a proteolytic enzym 

 obtained from Bacillus jyyocyaneus. A study was made oi the effect of this enzym 

 upon a number of pathogenic bacteria, but the anthrax bacillus was finally selected 

 as being the niost favorable for this study. From inoculation experiments the 

 authors believe it was demonstrated in the case of anthrax that a cure or artificial 

 immunity is brought about by the dissolution t)f the specific bacteria by means of 

 l)ai'teriolytic enzyms. It has generally been Ijelieved that these enzyms exist only 

 in the animal body. The authors were able, however, to produce the substances 

 artificially. 



A method of curing anthrax in horses, M. L. Yudin {Arch. Vet. Nauk.,30 

 {1900), No. 6, III, pp. 106-110) . — The author gives a description of a method of curing 

 anthrax in horses which was adopted in the Russian fifth army corps in 1830. Good 

 success is reported from the application of this method. 



New experiments in vaccinating reindeers, N. I. Ekkert {Arch. Vet. Nauk., 30 

 {1900), No. 4, J I, i>i>. 145-194). — The author conducted an extensive series of exper- 

 iments in innnunizing reindeer against anthrax. As a result of these experiments, 

 it is concluded that it is po.ssible to confer immunity against anthrax upon reindeer 

 by means of vaccination. In the extensive tundra regions of the government of 

 Archangel a method for i)roducing immunity is recjuired which can be applied on a 

 large scale and in a raj)iil manner. The veterinary department is engaged in solving 

 the jiroblems presented l)y these peculiar conditions. 



Malignant catarrhal fever of cattle, O. Oppexheim {Berlin. Tierdrztl. Wchnschr., 

 1900, No. 8, pp. 87, 88) . — From a careful study of a number of cases of this disease 



