596 EXPEEIMENT STATION RECORD. 



Immunization against rabies by means of normal nerve tissue, 

 A. AuJESZKY {CenthL Bald. a. Par., 1. Alt., 27 {1900), Na. 1. pp. b- 

 10). — Two dogs, weighing 6 and 5.5 kg., respectively, received a h3'po- 

 dermic injection dail}^ from January 2-i to Februar}' 11 of 10 cc. of an 

 emulsion which had been prepared from the spinal cord of healthy- 

 cattle, in normal salt solution. On February 15 the dogs were inocu- 

 lated in the ear with rabies virus. Injections were continued until 

 February 26, so that each dog during the course of 34 days received 

 30 gm. of spinal cord. The control rabbit died on the thirty-fifth day, 

 while the dogs remained health}'. 



Three dogs, weighing 8, 8.7, and 6.5 kg., respectively, received injec- 

 tions of normal nerve tissue as in the previous experiment. Ten days 

 after the beginning of these injections the}' were inoculated in the ear 

 with rabies virus. The dogs showed symptoms of rabies sooner than 

 the control animals. 



Three other dogs, weighing 6, 8, and 5 kg., respectively, received 

 injections of nerve substance as in the other experiments. When 

 inoculated with laboratory rabies virus, the dogs remained well, but 

 the control animal was also unaffected. When bitten by a rabid dog, 

 all showed symptoms of the disease within a short time. 



From these investigations it is concluded that hypodermic injections 

 with emulsions of normal nerve tissue are not sufficient to protect 

 animals against the more virulent rabies virus. ' In the first-mentioned 

 experiments, where this method seemed to be sucessful, the virulence 

 of the rabies virus was not determined, and it is possible that it was 

 not strong enough to produce rabies. 



The prophylaxis of malarial fever by means of protection against mosqui- 

 toes, E. Di Mattei {Centhl. Bnkt. u. Far., 1. AbL, 28 {1900), No. 6-7, pp. 189-195).— 

 An experiment was conducted by the author on 4 men in Catania for the purpose 

 of determining whether malarial fever could be contracted without the agency of 

 mosquitoes. The 4 men who submitted to the experiment slept in an exceedingly 

 malarial district for 32 nights with doors and windows open, but covered with close 

 netting which prevented the entrance of all mosquitoes, and no case of malaria devel- 

 oped in any of the 4 men. 



The influence of tetanus toxin on the central nervous system, ]M. Joukowsky 

 {Ann. List. Pasteto', 14 {1900), Xo. 7, pp. 464-478, pi. 1) . — In cases of poisoning from 

 tetanus toxin, modifications in the nerve cells of the medulla and to a certain extent 

 in those of the cerebrum are to be noted. The modifications of the cell nuclei are 

 varialjle and can not be considered characteristic of this disease. Another patho- 

 logical condition is more uniformly observed and consists in the accunuilation of 

 mononuclear migratory cells around the nerve cells. These migratory cells penetrate 

 the protoplasm of the nerve cells, especially in the anterior group of cells of the 

 anterior cornua. This phenomenon is to be considered as a phagocytosis. 



Text-book of special pathology and therapy of domesticated animals, F. 

 Friedbergek and E. Fuohxer {Lehrhnch der .ipeciellen Pathologie mid Therapk der 

 Hausthiere. Stuttgart : Ferdinand Fnke, 1900, 5. ed., ml. 1, pp. 867). — This volume con- 

 tains an elaborate discussion of the various diseases of the digestive organs, liver, 

 diaphragm, s})lcen, urinary and genital organs, heart and larger blood vessels, skin, 

 locomotor organs, and nervous system. 



Analyses of urine for the detection of antipyretics, A. Petermaxx {Bid. Sta. 



