C. ESTABLE 



321 



investigations of Bartelmcz, Bartclmcz and Hocrr Bodian (1937-40) led to 

 the definition oi a synapse as a contact between membranes with 

 mitochondria subjacent in the prc-synaptic region (Bartehiiez, 191 5; 

 Bartehnez and Hoerr, 1933; Bodian, 1937; Bodian, 1942; Held, 1H97). 





N 





N 



^ 



Y-". 



^1...«A 



Fu,. 12 

 Somato-scimatic contacts. Low inai;nification clectroninicrograph of the rat ccrcbcllmu 

 granular layer showing the intimate soniato-soniatic relationship between grains. N. Nuclei, 

 ni — mitochondria ■ 16.000. 



This definition, based on structure only, is not satisfactory, as it excludes 

 incontrovertible synaptic types. 



(/)) The microvesicles having been discovered by Sjoestrand — and by him 

 called 'granules' — in the synapse of cones and rods with the dendrites of 



