HOST-PARASITE RELATIONS: INTESTINAL PROTOZOA 



other hand, he is not comfortable in the abdominal re- 

 gion. He is, as we say, 'bowel conscious.' He may have 

 considerable flatulence. He may or may not complain 

 of definite soreness in the right lower quadrant, in the 

 right upper quadrant, or in the region of the splenic 

 flexure. He may complain of neuritic symptoms, pain 

 alpng the course of some particular nerve or nerves. He 

 may complain of basal headache, or of pain and aching 

 in the region of joints. He may have considerable diges- 

 tive disturbance, referable to the upper abdomen, that 

 leads to the clinical suspicion of hyperacidity, hypoacid- 

 ity, gastric and duodenal ulcers, chronic pancreatitis, 

 chronic cholecystitis, chronic duodenitis or chronic hepa- 

 titis. He may complain of cough and expectoration, with 

 bloody sputum. He may complain of rapid pulse, and one 

 may see mild tachycardias. He may complain of much 

 nervousness, and one may find in him symptoms of a 

 subacute or chronic thyroiditis. He may complain of de- 

 fective vision, and one may find greatly impaired vision 

 with or without definite iritis. Some may complain of 

 disabling loss of memory, while others show various neu- 

 roses. One may find also the grosser lesions of liver ab- 

 scess, lung abscess, brain abscess, skin ulcers, etc. The 

 matter can be summed up by saying that in chronic 

 amebiasis we are dealing with a disease entity as protean 

 as syphilis." Boyers, Kofoid & Swezy (1925). 



Acton and Knowles (1924) are also among those who 

 believe the "healthy" carrier is not always free from 

 clinical symptoms. They "recognize two well marked 

 types of E, histolytica carriers; the first the thin, lean, 

 cadaverous individual whose food assimilation is inade- 



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