ANTIBODIES II 



25 



TABLE 2-4 

 Serological Specificity of Stereoisomers of Tartaric Acid 



" Symbols indicate degree of precipitation when antisera for conjugated proteins 

 containing isomers on left were mixed with proteins containing isomers shown on 

 right. The symbol -|- + + indicates strong positive reaction ; 0, negative reaction. 



carbon atom (Fig. 2-9), could be distinguished serologically. Later 

 work (Avery, Goebel, and Babers, 1932) even showed that the alpha 

 and beta anomers of glucose, when converted to the />-aminophenyl- 



eCHgOH 



H.OH 



H,OH 



H OH H OH 



D- Glucose D- Galactose 



Fig. 2-9. 



glucosides, diazotized, and coupled to a protein, gave rise to different 

 antibodies (Fig. 2-10). The distinction was not as sharp as between 



N = N — 



CH,OH 



CH2OH 



Fig. 2-10. a- and /3-D-glucoside haptens. 



