ANTIGENS 43 



TABLE 3-4 

 Inhibition of Heterologous Reaction by Homologous Hapten* 



phthalyl glycine-leucine (Fig. 3-5), which they referred to as GIL, 

 as hapten they obtained two distinct antibodies. One reacted with 

 w-aminobenzoyl glycine (G) and the other with 77?-aminobenzoyl 



NH, 



HOOCCH2NOCI IcONHCHCOOH 



CH2CH(CH3)2 

 GIL 



Fig. 3-5. 



leucine (L) (Fig. 3-6). The anti-G of stich a serum was not re- 

 movable with antigen containing only L, and the anti-L was not 

 removable with antigen containing only G. Evidently the two amino 



NH2 NH2 



I ICONHCHCOOH 



CH2CH(CH3)2 

 L 

 Fig. 3-6. 



acid residues in GIL were too far apart to be spanned simtiltaneously 

 by a typical antibody determinant, although there was some evidence 

 for the presence in the antiserum of a slight amount of a special 



