SALMONELLA ANTIGENS 



109 



Abequose 

 ( 3,6- Dideoxy- D- galactose) 



H,OH 



Ascorylose 

 (3,6- Dideoxy- L- mannose) 



Fig. 8-L Five naturally occurring 3,6-dideoxyhexoses. 



terminal dideoxy sugars did play an important antigenic role, as ex- 

 pected. Each Salmonella species produces only one such sugar, and 

 this sugar is characteristic of the group. A, B, etc., into which the 

 species falls in the Kaufifmann- White scheme. Paratose is characteris- 

 tic of species in group A, for example, and colitose of group O (Table 

 8-4). 



It has been further shown (Staub, Tinelli, Liideritz, and Westphal, 

 1959) that different dideoxyhexoses function as terminal groups 

 of various antigenic factors of the Kauffmann- White scheme, abequose 

 being the terminal unit of antigen 4 of group B, tyvelose of antigen 9 

 of group D, and colitose of antigen 35 of group O. 



There seems to be no evidence that more than one of these 3,6- 

 dideoxyhexoses occurs in the endotoxin of any one species of 

 Salmonella. When a 3,6-dideoxyhexose does occur it always occupies 

 the terminal position in a side chain of the antigenic determinant of 



