152 



ALPHABETICAL COMPILATION 



TABLE 13 



EFFECTIVE CONCENTRATIONS OF ANAESTHETICS TO ARREST CLEAVAGE OF 

 ARBACIA PUNCTULATA EGGS 



From R. S. Lillie 1914b, J. Biol. Chem. 17 : 139 



Ethyl alcohol 

 n-Propyl alcohol 

 Iso-propyl alcohol 

 n-Butyl alcohol 

 f-Amyl alcohol 

 Capryl alcohol 

 Methyl urethane 

 Ethyl urethane 

 Phenyl urethane 

 Ethyl ether 

 Chloroform 

 Chloral hydrate 

 Chloretone 

 Nitromethane 

 Acetonitrile 

 Ethyl nitrate 

 Paraldehyde 

 Chloralose 

 Acetanilide 

 Phenyl urea 



ca. 5 V. % (0.87 M) 

 ca. 2 V. % (0.27 M) 

 ca. 3 V. % (0.4 M) 

 ca. 0.8 V. % (0.086 M) 

 ca. 0.4 V. % (0.037 M) 

 ca. 0.015 V. % (0.00 1 M) 

 2-2.5 % (0.27-0.33 M) 



I -5-1 -75% (0.15-0-19 M) 

 0.08-0.1 % (0.005-0.006 M) 

 0.5-0.6 V. % (0.05-0.06 M) 

 ca. 0.06 % (V12 sat.) (0.005 M) 

 0.1 -0.1 2 % (0.006-0.007 M) 

 0.2-0.25 % (0.008-0.01 M) 

 ca. 2. V. % (0.42 M) : unfavorable 

 ca. 2. V. % (0.5 M) : unfavorable 

 ca. 0.25 V. % (0.025 M) • unfavorable 

 2-3 V. % (0.15-0.2 M) : unfavorable 

 ineffective in sat. sol. {ca. 0.6 %) 

 ineffective in sat. sol. {ca. 0.5 %) 

 ineffective in sat. sol. {ca. 0.5 %) 



TABLE 14 



CRITICAL ANAESTHETIC CONCENTRATIONS OF URETHANES FOR REVERSIBLY SUPPRESSING 

 CLEAVAGE IN ARBACIA PUNCTULATA EGGS 



From E. B. Harvey per E. N. Harvey, 1932 a, Biol. Bull. 52 : 151 



Ethyl urethane 

 N-propyl urethane 

 Isopropyl urethanes 

 N-butyl carbamate 

 Isoamyl carbamate 

 Phenyl urethane 



0.15-0.2 M 

 0.07 M 

 0.1 M 

 0.025 ^ 

 0.0 1 M 

 0.00125-0.0025 M 



Spiral asters formed in Paracentrotus lividus with phenyl urethane (Painter, 19 16); 

 with KCN (Runnstrom, 1930, p. 155). Spiral asters formed with high centrifugal 

 force in Psammechinus microtuberculatus (E. B. Harvey, 1935a). See classical study of 

 Mark ( 1 88 1 ) on spiral asters normally occuring in Limax campestris. 



Rhythms. — In mitotic cycle, of sensitivity to anaesthetics. With ether (Spaulding, 

 1904); higher alcohols (Baldwin, 1920); many anaesthetics (Heilbrunn, 1920 a). 



Gastrulation. — Effect of alcohols (Waterman, 1936). 



Ciliary Activity. — Of blastulae and plutei stopped by chloretone (chlorobutanol) ; 

 use a small amount of saturated solution in sea water added to swimming larvae 

 (E. B. H.). By magnesium sulphate (E. B. H.) ; widely used to quiet marine organisms 

 (Mayor, 1909; R. S. Lillie, 1916c; Heilbrunn, 1920b, 1934, 1952, p. 528); mag- 

 nesium anaesthesia antagonised by calcium (Heilbrunn, 1952, p. 589). 



