XVIU CONTENTS 



CONN'ERSION OF ACTIVE PRINCIPLES i O ToXOID Ill 



Reacung Potency of PREc:iiMrArE.s anb Supernatani Ki rins 

 Derived from Mixtures of Ac:hve Bacterial Filiraies wiiii 

 Immune Sera 113 



Neutralization of Active Principles in "Multiple Propor- 

 tions" 117 



An Antibody Auxiliary 10 Serum Neuiralization of Menin(;o- 

 coccus Reacting Factors 1 20 



Reactivating Effect of Blood Sera Upon Completely Neu- 

 tralized Toxic Filirates 123 



Recapitulation 127 



(]]}(( l)ier V 



IMMUNITY TO THE PHENOMENON OF LOCAL 

 SKIN REACTIVITY 



Natural Immunity of Rabbits 130 



Spontaneous and Acquired Active Immunity as Determined by 



THE Use of Graded Amounts of Active Principles 133 



Spontaneous Inmiunity; Active Acquired Immunity. 



Phenomenon of Local Skin Reacitvity to Bacterial Fil- 

 trates IN Animals Other Than the Rabbit 138 



Passive Immunity to Active Principles 140 



Recaphulahon 144 



dial) fey 17 



ROLE OF INFLAMMATION IN THE PHENOMENON OF 



LOCAL SKIN REACTIVITY— OPTIMUM CONDITIONS 



FOR REPRODUCTION OF THE PHENOMENON 



Introduction 146 



Effects of Intradermal Injection of Bacterial Produc;is in 



Their Relation to the Phenomenon 147 



Skin-preparatory Effect of Non-Bacterial Substances 151 



Skin-preparatory Potency of Sterile Tryptic Digest Broth; Skin- 

 preparatory Potency of Turpentine; Skin-preparatory Potency 

 of Gum Tragacanth, Crystalline Egg Albumin, Blood Sera, 

 Sodium Arsenate, Spirits of Nitroglycerine, India Ink; Skin- 

 preparatory Potency of Mixtures of Animal Protein Antigens 



