CONTENTS XIX 



with Antibodies; Unpublished Observations on the Skin- 

 preparatory Effect of Various Non-bacterial Substances: Spleen, 

 liver, adrenals, kidney and brain extracts; sera treated with 

 agar; calcium gluconate; xylol; eserine salicylate; cantharidin 

 plaster; hypertonic NaCl solution; silver nitrate; histamine; 

 acetylcholine; allylamine; Croton oil; urethane ethyl; calcium 

 chloride; antispleen sera; Sid^stances Studied by Others. 

 Effect of Non-bacterial Substances Upon the State of Re- 

 activity TO Bacterial Filtrates 160 



Ascorbic Acid; Alypin; Cocaine; Acetylcholine; Pvridine; Anti- 

 platelet Serum; Prolan; General Anesthesia; India Ink. 

 Studies on the Behavior of Capillaries in Sites Prepared 



WITH Active Principles 162 



Morphological Studies on the Phenomenon 164 



Route of Injection of Reacting Factors and iNCUBArioN 

 Period Necessary for Elicitaiion of the State of Reac:- 



TiviTY 175 



Fate of Active Principles Injected Into the Blood Stream . . 182 

 Recapiiulation 184 



Chapter VII 



METHODS OF ELICITATION OF THE PHENOMENON 

 OF LOCAL TISSUE AND ORGAN REACTIVITY 



Perivascular Reactivity 186 



Local Vascular Reactivity 193 



Elicitation of Renal Vascular Reactivity; Elicitation of Vas- 

 cular Reactivity in the Rabbit's Ear: Preparatory intravenous 

 injections of active principles accompanied by chilling; pre- 

 paratory intravenous injections of active principles in xylol- 

 treated ears; preparatory intravenous injections of active 

 jMinciples combined with ethyl urethane, acetylcholine, pilo- 

 carpine hydrochloride, atropine, calcium gluconate and guinea 

 pig liver extract; preparatory intravenous injections of active 

 principles in combination with histamine; preparatory in- 

 travenous injections of active principles combined with 

 adrenalin; preparatory intravenous injections of active princi- 

 ples in combination with pituitrin; preparatory intravenous 

 injections of active principles accompanied by application of 

 heat; preparatory intravenous injections of active principles 

 combined with tcsticidar extract. 



