248 LOCAL ILSSLL REACTIVITY 



on tlic (Icnclopniciit ol lliis tumor. Inasimi(li as ihc liliiates of 

 li. (')il(') il tdis arc (a])al)l(' ol ('li(itiii<; llic plK'Honicnon ol local 

 (UtaiK'oiis rea(li\ilN in lahhils in lii<'li dilntions and (he (ultnre 



Fk;. 26. Section ol twehe day okl tumor twenty-four hours after intravenous in- 

 icclion of I c.c. of a B. enteritidis filtrate. Viable tumor tissue is sharply demarcated 

 l)y /one of hemorrhage and necrosis. X 220. (Shwartzman, 1936(7.) 



filtrates of Staphylococcus aureus produce no effect, it is highly 

 suggestive that the inhibitory influence of an infecting micro- 

 organism on sarcoma 180 is conditioned by its ability to secrete the 

 active principles of the phenomenon. (Shwartzman, ig^Qa.) 



In recent experiments of Eisen (1936), an infection in the 

 tumor was induced by the Danysz bacillus highly pathogenic for 



