PROTOZOA IN THE CIRCULATORY SYSTEM 93 



Maiirer's dots, which are coarser in size and fewer in num- 

 ])er dian Schiiffner's dots found in the erythrocyte infected 

 bv P. vivax. In aliout 12 hours after the attack of fever, 

 these schizonts disappear from the periplieral blood. 

 2. Growth and schizogonic stages. These are found only 



'^ at- o 



o 





t 



f 



Q 7 8 S fO 



Fig. 24. Plasmodium falciparum. X 1150. (original) 



1. Three ring forms in an erythrocyte. 



2. A somewhat grown schizont in 



an erythrocyte with Maurer's dots. 

 3-6. Growth and schizogonic stages. 

 7, 8. Merozoite formation. 



9. A macrogametocyte. 



10. A microgametocyte. 



in the capillaries of various internal organs As the schiz- 

 onts grow, the cytoplasm becomes denser. Haemozoin 

 granules which are much darker than those in other spe- 

 cies, become grouped into a compact mass (in contrast to 

 the scattered granules in the other two species). When the 

 schizont reaches the size about two-thirds of the infected 

 erythrocytes (about 5m), nuclear division begins and finally 

 8-24 or more nuclei are produced (Fig. 24, 5, «). Thus 8-24 

 small merozoites are formed. When these merozoites are 



