EVALUATION OF METABOLIC PATHWAYS 37 



1 C02 



2 COOH TCA 



■^ 2 CO2 



3 CH3 cycle 



4 CO2 



5 COOH TCA ^ g 



6 CH3 cycle 



3 CO2 



6 CO2 



-^ 2 CO2 



3 CO2 



6 COoetc. 



4 C 4 CO2 



"5 C '^^f > 5 CO2 



" 6 C ^'^'^ 6 CO2 



22 CH3 _co 22 CH3 TCA ^ 22 CO2 



33 CO 7;^ 33 COOH cycle 33 CO2 



EMP _ ^^^TT +[^J 



-^ 32 COOH 



32 CO2 



44 COOH ^^ 44 CO2 

 55 CO 



+ [0] 

 66 CH3 55 COOH TCA ^ 55 CO2 



66 CH3 cycle 66 CO2 



Fig. 2.5. Relative rates of CO^, production from glucose via different 

 pathways; identity of glucose carbons in other intermediates. 



EMP = Glycolysis (Embden-Meyerhof-Parnas) 

 ED = Entner-Doudoroff 



HMP = Hexose Monophosphate Pathway (phosphogluconate cleavage) 

 (including pentose cycle) 



