90 PROTOZOAN PARASITISM 



lined by Cort (1928) emphasizes the present day 

 idea that emetine is not to be depended upon to elim- 

 inate the amoebic infection but is most valuable in 

 controlling the active phase of the disease. He rec- 

 ommends emetine in 1 grain dosage intra-muscularly 

 daily for 7 days. After an interval of 1 week another 

 series of 5 injections are given; then 2 series of 2 to 3 

 injections at intervals of 1 month. With frequent 

 stools or loss of sphincter control, use chiniofon 

 (yatren) enemas, one a day, with bismuth or opium, 

 as indicated. 



When the stools are less frequent give acetarsone 

 (stovarsol) by mouth, (as well as emetine) one 4 

 grain tablet twice a day for not more than 6 or 7 days. 

 Then continue with chiniofon (yatren) pills, first 

 two 4 grain tablets twice daily, increasing to four pills 

 three times a day. Repeat this course at the end 

 of one month. 



Cort considers emetine a specific for amoebic hepa- 

 titis but not for intestinal amoebiasis, which inter- 

 preted appears to mean that the effect of the amoebic 

 products, from the ulcers of the intestine, upon the 

 liver is counteracted in some way by the drug, that 

 again the influence of emetine is more on the host 

 than the parasite. 



In Cort's experience abscesses of the liver should 

 be aspirated and then treated with emetine, while in 

 case of poor surgical risk on account of the amoebia- 

 sis, emetine may convert into a state favorable to 

 operation. 



